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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KAKPPKKPESSAEQ) corresponding to the internal amino acids of AIRE|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, porcine and rat based on sequence homology.
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay . Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AIRE; AIRE1; APECED; APECED protein homolog; APS1; APSI; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; autoimmune regulator; autoimmune regulator (APECED protein); autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE; autoimmune regulator AIRE1a; PGA1
AIRE; AIRE1; APECED; APS1; APSI; PGA1