AIRE Antibodies

Antibodies that detect AIRE can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target AIRE in Human, Mouse, Rat and Porcine samples. Our AIRE polyclonal and... Antibodies that detect AIRE can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target AIRE in Human, Mouse, Rat and Porcine samples. Our AIRE polyclonal and monoclonal antibodies are developed in Rabbit, Rat,... Antibodies that detect AIRE can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target AIRE in Human, Mouse, Rat and Porcine samples. Our AIRE polyclonal and monoclonal antibodies are developed in Rabbit, Rat, Goat and Mouse. Find the AIRE antibody that fits your needs. Choose from 1 of 25 AIRE antibodies, which have been validated in experiments with 116 publications and 112 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen... Antibodies that detect AIRE can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target AIRE in Human, Mouse, Rat and Porcine samples. Our AIRE polyclonal and monoclonal antibodies are developed in Rabbit, Rat, Goat and Mouse. Find the AIRE antibody that fits your needs. Choose from 1 of 25 AIRE antibodies, which have been validated in experiments with 116 publications and 112 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

AIRE is a transcriptional regulator protein that binds to DNA as a dimer and tetramer, but not as a monomer, and may be involved in the regulation of gene expression. A nuclear protein, AIRE is a 545 amino acid protein with an HSR domain, two PHD type zinc fingers, and a SAND domain, and may be present in soluble high-molecular-weight complexes. It may form homodimer, homotetramer and also nuclear bodies and interacts with the transcriptional coactivator CBP and CREBBP. Three isoforms of AIRE are reported and one of them is predicted to be a candidate for nuclear-mediated decay (NMD). AIRE is involved in immune regulation and is known to mediate E3 ubiquitin ligase activity. Defects in AIRE are responsible for the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Synonyms

Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1

AIRE Antibodies

Target Information

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