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Proteintech
AMIGO3 Polyclonal Antibody
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Product Details
21278-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMIGO3 Fusion Protein Ag15790 (221-504 aa encoded by BC110418)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LPCDCRLYH LLQRWHQRGL SAVRDFAREY VCLAFKVPAS RVRFFQHSRV FENCSSAPAL GLERPEEHLY ALVGRSLRLY CNTSVPAMRI AWVSPQQELL RAPGSRDGSI AVLADGSLAI GNVQEQHAGL FVCLATGPRL HHNQTHEYNV SVHFPRPEPE AFNTGFTTLL GCAVGLVLVL LYLFAPPCRC CRRACRCRRW PQTPSPLQEL SAQSSVLSTT PPDAPSRKAS VHKHVVFLEP GRRGLNGRVQ LAVAEEFDLY NPGGLQLKAG SESASSIGSE GPMTT (221-504 aa encoded by BC110418)
Target Information
Amphoterin induced gene and ORF 3 (AMIGO3) is a gene located on chromosome 3p21.31, encoding a member of the AMIGO family of proteins involved in cell adhesion, axon guidance, and neuronal signaling. AMIGO3 is primarily expressed in the central nervous system, playing a crucial role in neural development and the maintenance of neural circuits. Functionally, AMIGO3 contributes to neuronal growth and synapse formation, impacting processes such as neural plasticity and signal transduction. The protein's activity facilitates interactions with other neuronal surface proteins, influencing axon pathfinding and connectivity. Aberrant expression or mutations in AMIGO3 have been linked to neurological disorders and neurodegenerative diseases, suggesting its significance in neural health and pathology. Research into AMIGO3 continues to explore its potential therapeutic applications in promoting neural repair and modulating synaptic functions, offering insights into strategies for addressing nervous system disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adhesion molecule with Ig-like domain 3; alivin 3; Alivin-3; AMIGO-3; AMIGO3; amigo3 {ECO:0000312|EMBL:AAO48952.1, ECO:0000312|RGD:631413}; amphoterin induced gene and ORF 3; amphoterin-induced gene and ORF 3; Amphoterin-induced protein 3; MGC120552; transmembrane protein AMIGO3
Gene Aliases: ALI3; AMIGO-3; AMIGO3; E430002N15Rik; KIAA1851; mKIAA1851; UNQ6084/PRO20089
UniProt ID: (Human) Q86WK7, (Rat) Q80ZD5, (Mouse) Q8C2S7
Entrez Gene ID: (Human) 386724, (Rat) 316003, (Mouse) 320844
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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