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Invitrogen
AMIGO3 Polyclonal Antibody
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Product Details
PA5-48013
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse AMIGO3 Thr20-Pro378
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant mouse AMIGO2 is observed and less than 2% cross-reactivity with recombinant human AMIGO1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Amphoterin induced gene and ORF 3 (AMIGO3) is a gene located on chromosome 3p21.31, encoding a member of the AMIGO family of proteins involved in cell adhesion, axon guidance, and neuronal signaling. AMIGO3 is primarily expressed in the central nervous system, playing a crucial role in neural development and the maintenance of neural circuits. Functionally, AMIGO3 contributes to neuronal growth and synapse formation, impacting processes such as neural plasticity and signal transduction. The protein's activity facilitates interactions with other neuronal surface proteins, influencing axon pathfinding and connectivity. Aberrant expression or mutations in AMIGO3 have been linked to neurological disorders and neurodegenerative diseases, suggesting its significance in neural health and pathology. Research into AMIGO3 continues to explore its potential therapeutic applications in promoting neural repair and modulating synaptic functions, offering insights into strategies for addressing nervous system disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alivin 3; Alivin-3; AMIGO-3; amigo3; amphoterin induced gene and ORF 3; Amphoterin-induced protein 3; MGC120552
Gene Aliases: Ali3; Amigo3; E430002N15Rik; Kiaa1851; mKIAA1851
UniProt ID: (Mouse) Q8C2S7
Entrez Gene ID: (Mouse) 320844
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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