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Proteintech
TACSTD2/TROP2 Monoclonal Antibody (5A6B1), APC
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Product Details
APC-68141
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
5A6B1
Immunogen
TACSTD2/TROP2 fusion protein Ag25775
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Affinity chromatography
Storage buffer
PBS with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAG
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40kD glycoprotein, identified by monoclonal antibody GA733; Cell surface glycoprotein Trop-2; cell surface glycoprotein TROP2; epithelial glycoprotein-1; GA733; gastrointestinal tumor-associated antigen GA7331; lymphocyte antigen 97; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; TACD2; TACSTD2; trophoblast cell surface antigen 2; Tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2; unnamed protein product
Gene Aliases: C80403; EGP-1; EGP1; GA733-1; GA7331; GP50; Ly97; M1S1; TACSTD2; TROP2
UniProt ID: (Human) P09758, (Mouse) Q8BGV3
Entrez Gene ID: (Human) 4070, (Mouse) 56753
visual perception
negative regulation of epithelial cell migration
regulation of epithelial cell proliferation
negative regulation of stress fiber assembly
ureteric bud morphogenesis
negative regulation of branching involved in ureteric bud morphogenesis
negative regulation of substrate adhesion-dependent cell spreading
negative regulation of ruffle assembly
negative regulation of cell motility
positive regulation of stem cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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