The antibody is specific to ARX. This is a rabbit polyclonal antibody raised against a peptide mapping within human ARX.
Arx contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This protein is thought to be involved in CNS development. Mutations in the Arx gene cause X-linked mental retardation and epilepsy.
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Protein Aliases: Aristaless-related homeobox; aristaless-related homeobox, X-linked; cancer/testis antigen 121; Homeobox protein ARX
Gene Aliases: ARX; CT121; EIEE1; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS
Molecular Function: homeodomain transcription factor