Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human ARX (NP_620689.1). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
3.07 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2854826 |
Sequence of this protein is as follows: LLRQPTPAVE GAVASGALAD PATAAADRRA SSIAALRLKA KEHAAQLTQL NILPGTSTGK EVC
Arx contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This protein is thought to be involved in CNS development. Mutations in the Arx gene cause X-linked mental retardation and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Aristaless-related homeobox; aristaless-related homeobox, X-linked; arx {ECO:0000250|UniProtKB:Q96QS3}; cancer/testis antigen 121; Homeobox protein ARX
Gene Aliases: ARX; CT121; EIEE1; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS; RGD1562672
UniProt ID: (Human) Q96QS3, (Mouse) O35085, (Rat) A6YP92
Entrez Gene ID: (Human) 170302, (Mouse) 11878, (Rat) 317268
Molecular Function:
homeodomain transcription factor
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