PA5-32180 targets ATG12 in IHC (P), Immunofluorescence and Western Blot applications and shows reactivity with Human, Rat and mouse samples.
The PA5-32180 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 187 of Human ATG12.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
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Protein Aliases: APG12; Apg12 (autophagy; Apg12 (autophagy, yeast) homolog; APG12-like; APG12L; ATG12 autophagy related 12 homolog; autophagy-related 12; Autophagy-related protein 12; FBR93; HAPG12; Ubiquitin-like protein ATG12; yeast) homolog
Gene Aliases: 4931423H11Rik; A330058M13Rik; APG12; APG12L; ATG12; Atg12l; FBR93; HAPG12