Proteintech

ATG5 Polyclonal Antibody

ATG5 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

ATG5 Antibody (10181-2-AP) in ICC/IF

IF result of anti-ATG5 (10181-2-AP) with E15 mouse cortical neurons.

ATG5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

10181-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 209 publications 209 publications

Immunohistochemistry (IHC)

View 19 publications 19 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 21 publications 21 publications

Flow Cytometry (Flow)

Assay-dependent

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Not applicable (N/A)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ATG5 Fusion Protein Ag0214 (28-275 aa encoded by BC002699)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is raised against 28-275 amino acids of human ATG5. It can recognize the ATG5-ATG12 complex (55 kDa) which can be truncated and generate a 40-45 kDa band. 10181-2-AP also recognizes the free ATG5 (32 kDa).

Immunogen sequence: TEREAEPYY LLLPRVSYLT LVTDKVKKHF QKVMRQEDIS EIWFEYEGTP LKWHYPIGLL FDLLASSSAL PWNITVHFKS FPEKDLLHCP SKDAIEAHFM SCMKEADALK HKSQVINEMQ KKDHKQLWMG LQNDRFDQFW AINRKLMEYP AEENGFRYIP FRIYQTTTER PFIQKLFRPV AADGQLHTLG DLLKEVCPSA IDPEDGEKKN QVMIHGIEPM LETPLQWLSE HLSYPDNFLH ISIIPQPTD (28-275 aa encoded by BC002699)

Target Information

ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process. ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation. Following conjugation to ATG12, the conjugate participates in the formation of autophagosome. ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD). The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton. Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells. Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Frontiers in bioengineering and biotechnology

Ding Q,Liu W,Liu X,Ding C,Zhao Y,Dong L,Chen H,Sun S,Zhang Y,Zhang J,Wu M

Sat Jul 16 00:00:00 UTC 2022

Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.

International journal of molecular sciences

Ji J,Li S,Jiang Z,Yu J,Sun Y,Cai Z,Dong Y,Sun X

Fri Sep 16 00:00:00 UTC 2022

Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.

Frontiers in immunology

Xia N,Zheng W,Jiang S,Cao Q,Luo J,Zhang J,Xu Y,Sun S,Zhang K,Chen N,Meurens F,Zhu J

Tue Nov 01 00:00:00 UTC 2022

Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Shi YX,Sun ZW,Jia DL,Wang HB

Fri Jul 01 00:00:00 UTC 2022

The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.

Cell death discovery

Li S,Gao L,Liu J,Guo C,Zheng J,Zhi K,Ren W

Thu Aug 25 00:00:00 UTC 2022

O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.

International journal of molecular sciences

Cao Y,Zhang M,Li Y,Lu J,Zhou W,Li X,Shi H,Xu B,Li S

Tue Nov 22 00:00:00 UTC 2022

Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.

Theriogenology

Ye N,Lv Z,Huang Z,Cheng Y,Wei Q,Shi F

Tue Mar 15 00:00:00 UTC 2022

Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy.

Cell communication and signaling : CCS

Sun Z,Liu D,Zeng B,Zhao Q,Li X,Chen H,Wang J,Rosie Xing H

Wed Mar 02 00:00:00 UTC 2022

Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.

Journal of Zhejiang University. Science. B

Lu J,Fu S,Dai J,Hu J,Li S,Ji H,Wang Z,Yu J,Bao J,Xu B,Guo J,Yang H

Wed Jun 15 00:00:00 UTC 2022

Loss of ATG5 in KRT14⁺ cells leads to accumulated functional impairments of salivary glands via pyroptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yu S,Wang H,Liu M,Pei F,Liu H,Zhang J,Zhang L,Li Q,Chen Z

Thu Dec 01 00:00:00 UTC 2022

Loss of ATG5 in KRT14⁺ cells leads to accumulated functional impairments of salivary glands via pyroptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yu S,Wang H,Liu M,Pei F,Liu H,Zhang J,Zhang L,Li Q,Chen Z

Thu Dec 01 00:00:00 UTC 2022

Loss of ATG5 in KRT14⁺ cells leads to accumulated functional impairments of salivary glands via pyroptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yu S,Wang H,Liu M,Pei F,Liu H,Zhang J,Zhang L,Li Q,Chen Z

Thu Dec 01 00:00:00 UTC 2022

Loss of ATG5 in KRT14⁺ cells leads to accumulated functional impairments of salivary glands via pyroptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yu S,Wang H,Liu M,Pei F,Liu H,Zhang J,Zhang L,Li Q,Chen Z

Thu Dec 01 00:00:00 UTC 2022

Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Yang D,Wu X,Wang W,Zhou Y,Wang Z

Sat Jan 01 00:00:00 UTC 2022

Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes.

Nature communications

Greene CJ,Nguyen JA,Cheung SM,Arnold CR,Balce DR,Wang YT,Soderholm A,McKenna N,Aggarwal D,Campden RI,Ewanchuk BW,Virgin HW,Yates RM

Thu Jun 02 00:00:00 UTC 2022

Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.

Signal transduction and targeted therapy

Meng Y,Qiu L,Zeng X,Hu X,Zhang Y,Wan X,Mao X,Wu J,Xu Y,Xiong Q,Chen Z,Zhang B,Han J

Fri Dec 09 00:00:00 UTC 2022

S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.

Food & function

Wang Y,Xu J,Wang Y,Xiang L,He X

Mon Feb 21 00:00:00 UTC 2022

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

Nature communications

Jin S,He X,Ma L,Zhuang Z,Wang Y,Lin M,Cai S,Wei L,Wang Z,Zhao Z,Wu Y,Sun L,Li C,Xie W,Zhao Y,Songyang Z,Peng K,Zhao J,Cui J

Sat Sep 03 00:00:00 UTC 2022

The effect of QiangGuYin on osteoporosis through the AKT/mTOR/autophagy signaling pathway mediated by CKIP-1.

Aging

Yuan Y,Sun J,Zhou H,Wang S,He C,Chen T,Fang M,Li S,Kang S,Huang X,Tang B,Liang B,Mao Y,Li J,Shi X,Liu K

Mon Jan 24 00:00:00 UTC 2022

Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.

BMC molecular and cell biology

Mei J,Sheng X,Yan Y,Cai X,Zhang C,Tian J,Zhang M,Zhou J,Shan H,Huang C

Mon Jun 27 00:00:00 UTC 2022

Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.

BMC molecular and cell biology

Mei J,Sheng X,Yan Y,Cai X,Zhang C,Tian J,Zhang M,Zhou J,Shan H,Huang C

Mon Jun 27 00:00:00 UTC 2022

Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.

Journal of translational medicine

Cao J,Chen C,Chen Q,Gao Y,Zhao Z,Yuan Q,Li A,Yang S,He Y,Zu X,Liu J

Wed Jul 06 00:00:00 UTC 2022

The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.

Life (Basel, Switzerland)

Guo S,Qi M,Li H,Cui Y,Qi C,Cheng G,Lv M,Zheng P,Liu J

Mon Jul 25 00:00:00 UTC 2022

Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.

Science (New York, N.Y.)

Jang W,Puchkov D,Samsó P,Liang Y,Nadler-Holly M,Sigrist SJ,Kintscher U,Liu F,Mamchaoui K,Mouly V,Haucke V

Fri Dec 16 00:00:00 UTC 2022

Selenomethionine alleviates NF-κB-mediated inflammation in bovine mammary epithelial cells induced by Escherichia coli by enhancing autophagy.

International immunopharmacology

Tao L,Liu K,Li J,Zhang Y,Cui L,Dong J,Meng X,Zhu G,Wang H

Thu Sep 01 00:00:00 UTC 2022

Degradation of lipid droplets by chimeric autophagy-tethering compounds.

Cell research

Fu Y,Chen N,Wang Z,Luo S,Ding Y,Lu B

Wed Sep 01 00:00:00 UTC 2021

CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.

Annals of the New York Academy of Sciences

Zheng J,Zhu X,He Y,Hou S,Liu T,Zhi K,Hou T,Gao L

Mon Feb 01 00:00:00 UTC 2021

Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5.

Cell proliferation

Li M,Shen Y,Xiong Y,Wang S,Li C,Bai J,Zhang Y

Wed Dec 01 00:00:00 UTC 2021

Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5.

Cell proliferation

Li M,Shen Y,Xiong Y,Wang S,Li C,Bai J,Zhang Y

Wed Dec 01 00:00:00 UTC 2021

Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles.

Developmental cell

Hao M,Yeo SK,Turner K,Harold A,Yang Y,Zhang X,Guan JL

Mon Feb 08 00:00:00 UTC 2021

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.

Cell death & disease

Han Y,Xiong S,Zhao H,Yang S,Yang M,Zhu X,Jiang N,Xiong X,Gao P,Wei L,Xiao Y,Sun L

Sat Oct 30 00:00:00 UTC 2021

Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.

Journal of hazardous materials

Zhu Q,Liu Z,Wang Y,Song E,Song Y

Sat Jun 05 00:00:00 UTC 2021

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Autophagy

Huang T,Xu T,Wang Y,Zhou Y,Yu D,Wang Z,He L,Chen Z,Zhang Y,Davidson D,Dai Y,Hang C,Liu X,Yan C

Mon Nov 01 00:00:00 UTC 2021

Autophagic Flux Unleashes GATA4-NF-κB Axis to Promote Antioxidant Defense-Dependent Survival of Colorectal Cancer Cells under Chronic Acidosis.

Oxidative medicine and cellular longevity

Liu X,Zhao M,Sun X,Meng Z,Bai X,Gong Y,Xu L,Hao X,Yang T,Wei Z,Zhang X,Guo H,Li P,Liu Q,Gong Y,Shi Y,Shao C

Fri Mar 04 00:00:00 UTC 2022

Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE^-/- mice.

Biochemical and biophysical research communications

Wu H,Feng K,Zhang C,Zhang H,Zhang J,Hua Y,Dong Z,Zhu Y,Yang S,Ma C

Fri Jun 11 00:00:00 UTC 2021

Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE^-/- mice.

Biochemical and biophysical research communications

Wu H,Feng K,Zhang C,Zhang H,Zhang J,Hua Y,Dong Z,Zhu Y,Yang S,Ma C

Fri Jun 11 00:00:00 UTC 2021

Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.

Frontiers in neuroscience

Yuan X,Yang Y,Xia D,Meng L,He M,Liu C,Zhang Z

Tue Feb 01 00:00:00 UTC 2022

Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.

Experimental and therapeutic medicine

Xu L,Zhu L,Liu P,Wu Z,Zou Z

Sun Aug 01 00:00:00 UTC 2021

Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.

Journal of experimental & clinical cancer research : CR

Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C

Tue Aug 24 00:00:00 UTC 2021

Taurine Alleviates Streptococcus uberis-Induced Inflammation by Activating Autophagy in Mammary Epithelial Cells.

Frontiers in immunology

Wang Z,Lan R,Xu Y,Zuo J,Han X,Phouthapane V,Luo Z,Miao J

Wed Sep 15 00:00:00 UTC 2021

The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.

Journal of ethnopharmacology

Chen C,Ding W,Li J,Geng X,Zhang H,Sun Y

Fri Oct 08 00:00:00 UTC 2021

LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.

Ecotoxicology and environmental safety

Zhang Y,Guo S,Wang S,Li X,Hou D,Li H,Wang L,Xu Y,Ma B,Wang H,Jiang X

Wed Sep 01 00:00:00 UTC 2021

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Toxicology

Gao L,Yang X,Liang B,Jia Y,Tan S,Chen A,Cao P,Zhang Z,Zheng S,Sun L,Zhang F,Shao J

Tue Mar 30 00:00:00 UTC 2021

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Toxicology

Gao L,Yang X,Liang B,Jia Y,Tan S,Chen A,Cao P,Zhang Z,Zheng S,Sun L,Zhang F,Shao J

Tue Mar 30 00:00:00 UTC 2021

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Toxicology

Gao L,Yang X,Liang B,Jia Y,Tan S,Chen A,Cao P,Zhang Z,Zheng S,Sun L,Zhang F,Shao J

Tue Mar 30 00:00:00 UTC 2021

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Toxicology

Gao L,Yang X,Liang B,Jia Y,Tan S,Chen A,Cao P,Zhang Z,Zheng S,Sun L,Zhang F,Shao J

Tue Mar 30 00:00:00 UTC 2021

Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.

Biochimica et biophysica acta. Molecular cell research

Yang X,Jin N,Wang Y,Yao Y,Wang Y,Li T,Liu C,Yu T,Yin H,Zhang Z,Cheng SY,Yue S

Mon Nov 01 00:00:00 UTC 2021

FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.

Frontiers in pharmacology

Li M,Zhao X,Yong H,Shang B,Lou W,Wang Y,Bai J

Sat Dec 25 00:00:00 UTC 2021

SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.

Frontiers in oncology

Wen D,Liu WL,Lu ZW,Cao YM,Ji QH,Wei WJ

Sun May 23 00:00:00 UTC 2021

DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.

Biochemical and biophysical research communications

Lu C,Wu B,Liao Z,Xue M,Zou Z,Feng J,Sheng J

Fri Jun 25 00:00:00 UTC 2021

LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.

Frontiers in cell and developmental biology

Gui Z,Zhao Z,Sun Q,Shao G,Huang J,Zhao W,Kuang Y

Fri Nov 19 00:00:00 UTC 2021

Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.

Autophagy

Feng X,Zhang H,Meng L,Song H,Zhou Q,Qu C,Zhao P,Li Q,Zou C,Liu X,Zhang Z

Mon Mar 01 00:00:00 UTC 2021

Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.

Autophagy

Feng X,Zhang H,Meng L,Song H,Zhou Q,Qu C,Zhao P,Li Q,Zou C,Liu X,Zhang Z

Mon Mar 01 00:00:00 UTC 2021

Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.

Microorganisms

Yuan L,Chu B,Chen S,Li Y,Liu N,Zhu Y,Zhou D

Tue Nov 16 00:00:00 UTC 2021

Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway.

Life sciences

Fan X,Zhou J,Yan X,Bi X,Liang J,Lu S,Luo L,Zhou D,Yin Z

Tue Jun 15 00:00:00 UTC 2021

UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.

Aging

Zhang M,Chen H,Qin P,Cai T,Li L,Chen R,Liu S,Chen H,Lin W,Chen H,Strickland AL,Xiong H,Jiang Q

Tue Sep 14 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.

British journal of pharmacology

Sun SY,Hu XT,Yu XF,Zhang YY,Liu XH,Liu YH,Wu SH,Li YY,Cui SX,Qu XJ

Tue Jun 01 00:00:00 UTC 2021

Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes.

International journal of molecular medicine

Xu T,Xu X,Chu Y,Jiang D,Xu G

Wed Dec 01 00:00:00 UTC 2021

H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.

Molecular medicine reports

Lin J,Wei J,Lv Y,Zhang X,Yi RF,Dai C,Zhang Q,Jia J,Zhang D,Huang Y

Mon Mar 01 00:00:00 UTC 2021

Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.

Frontiers in immunology

Chen L,Niu X,Qiao X,Liu S,Ma H,Shi X,He X,Zhong M

Fri Apr 08 00:00:00 UTC 2022

Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.

Pharmaceutical biology

Pi XJ,Zhao QQ,Wang JX,Zhang XL,Yuan D,Hu SS,He YM,Zhang CC,Zhou ZY,Wang T

Wed Dec 01 00:00:00 UTC 2021

Coibamide A kills cancer cells through inhibiting autophagy.

Biochemical and biophysical research communications

Shi W,Lu D,Wu C,Li M,Ding Z,Li Y,Chen B,Lin X,Su W,Shao X,Xia Z,Fang L,Liu K,Li H

Fri Apr 02 00:00:00 UTC 2021

Coibamide A kills cancer cells through inhibiting autophagy.

Biochemical and biophysical research communications

Shi W,Lu D,Wu C,Li M,Ding Z,Li Y,Chen B,Lin X,Su W,Shao X,Xia Z,Fang L,Liu K,Li H

Fri Apr 02 00:00:00 UTC 2021

Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.

Frontiers in chemistry

Shang Y,Wang Q,Li J,Liu H,Zhao Q,Huang X,Dong H,Chen W,Gui R,Nie X

Sat Apr 03 00:00:00 UTC 2021

OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.

ACS chemical neuroscience

Guo X,Bao X,Wang X,Liu D,Liu P,Chi T,Ji X,Zheng Z,Chen G,Zou L

Wed Nov 03 00:00:00 UTC 2021

Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.

Food & function

Qu L,Fu R,Ma X,Fan D

Mon Oct 04 00:00:00 UTC 2021

Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.

Biochemical and biophysical research communications

Liu A,Wang W,Lu Z,Liu Z,Zhou W,Zhong Z,Ye Q

Fri Apr 23 00:00:00 UTC 2021

6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.

European journal of nutrition

Pei XD,He ZL,Yao HL,Xiao JS,Li L,Gu JZ,Shi PZ,Wang JH,Jiang LH

Sun Aug 01 00:00:00 UTC 2021

Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.

Cell death & disease

Wang Y,Lu H,Sun L,Chen X,Wei H,Suo C,Feng J,Yuan M,Shen S,Jia W,Wang Y,Zhang H,Li Z,Zhong X,Gao P

Sat Oct 02 00:00:00 UTC 2021

Autophagy regulates functional differentiation of mammary epithelial cells.

Autophagy

Elswood J,Pearson SJ,Payne HR,Barhoumi R,Rijnkels M,W Porter W

Mon Feb 01 00:00:00 UTC 2021

Autophagy regulates functional differentiation of mammary epithelial cells.

Autophagy

Elswood J,Pearson SJ,Payne HR,Barhoumi R,Rijnkels M,W Porter W

Mon Feb 01 00:00:00 UTC 2021

Aristolochic acid I induces impairment in spermatogonial stem cell in rodents.

Toxicology research

Liu Y,He X,Wang Y,Zhou H,Zhang Y,Ma J,Wang Z,Yang F,Lu H,Yang Y,Deng Z,Qi X,Gong L,Ren J

Sat May 01 00:00:00 UTC 2021

The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.

Diabetes, metabolic syndrome and obesity : targets and therapy

Xu X,Chen B,Huang Q,Wu Y,Liang T

Sat Apr 16 00:00:00 UTC 2022

Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.

Acta biochimica et biophysica Sinica

Li Y,Liu M,Yi J,Song X,Zheng X,Liu D,Wang S,Chu C,Yang J

Tue Dec 29 00:00:00 UTC 2020

MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.

Life sciences

Liu J,Zhu Z,Liu Y,Wei L,Li B,Mao F,Zhang J,Wang Y,Liu Y

Sat Feb 01 00:00:00 UTC 2020

FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.

Pathology, research and practice

Zhao L,Kong X,Zhong W,Wang Y,Li P

Tue Sep 01 00:00:00 UTC 2020

Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.

Oncology letters

Yu X,Fan H,Jiang X,Zheng W,Yang Y,Jin M,Ma X,Jiang W

Thu Oct 01 00:00:00 UTC 2020

High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.

Acta histochemica

Ying C,Ying L,Yanxia L,Le W,Lili C

Sat Feb 01 00:00:00 UTC 2020

HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.

ACS applied materials & interfaces

He G,Pan X,Liu X,Zhu Y,Ma Y,Du C,Liu X,Mao C

Wed Oct 28 00:00:00 UTC 2020

Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.

Nutrients

Xuan H,Ou A,Hao S,Shi J,Jin X

Wed Jan 29 00:00:00 UTC 2020

Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.

Veterinary sciences

Zou YJ,Xu JJ,Wang X,Zhu YH,Wu Q,Wang JF

Fri Aug 14 00:00:00 UTC 2020

α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.

Experimental and therapeutic medicine

Wang X,Chi J,Huang D,Ding L,Zhao X,Jiang L,Yu Y,Gao F

Sat Feb 01 00:00:00 UTC 2020

HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.

Frontiers in cell and developmental biology

Zhan Y,Wang H,Zhang L,Pei F,Chen Z

Fri Dec 18 00:00:00 UTC 2020

NOD2/c-Jun NH₂-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.

Journal of bacteriology

Luo H,Wu X,Xu Z,Hao X,Wang Y,Li M

Wed Sep 23 00:00:00 UTC 2020

Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.

International journal of oncology

Yang Z,Chen Y,Wei X,Wu D,Min Z,Quan Y

Mon Jun 01 00:00:00 UTC 2020

PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation.

Free radical biology & medicine

Xu Y,Tang Y,Lu J,Zhang W,Zhu Y,Zhang S,Ma G,Jiang P,Zhang W

Fri Nov 20 00:00:00 UTC 2020

S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy.

Cell death & disease

Sun Z,Zeng B,Liu D,Zhao Q,Wang J,Rosie Xing H

Thu Aug 06 00:00:00 UTC 2020

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.

Frontiers in pharmacology

Xu Q,Fan Y,Loor JJ,Liang Y,Sun X,Jia H,Zhao C,Xu C

Thu Dec 31 00:00:00 UTC 2020

Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.

Innate immunity

Han L,Ma Q,Yu J,Gong Z,Ma C,Xu Y,Deng G,Wu X

Thu Oct 01 00:00:00 UTC 2020

Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.

Molecular medicine reports

Li R,Yang W,Hu X,Zhou D,Huang K,Wang C,Li Y,Liu B

Thu Oct 01 00:00:00 UTC 2020

The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.

Cell death & disease

Gao L,Wang Q,Ren W,Zheng J,Li S,Dou Z,Kong X,Liang X,Zhi K

Thu Jun 25 00:00:00 UTC 2020

Latcripin-7A, derivative of Lentinula edodes C_91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G₁ phase in breast cancer cells.

Applied microbiology and biotechnology

Din SRU,Zhong M,Nisar MA,Saleem MZ,Hussain A,Khinsar KH,Alam S,Ayub G,Kanwal S,Li X,Zhang W,Wang X,Ning A,Cao J,Huang M

Tue Dec 01 00:00:00 UTC 2020

CDKL3 Targets ATG5 to Promote Carcinogenesis of Esophageal Squamous Cell Carcinoma.

Frontiers in oncology

Zhou S,Zhang M,Zhou C,Wang W,Yang H,Ye W

Fri Sep 24 00:00:00 UTC 2021

Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.

Redox biology

Wang N,Liu H,Liu G,Li M,He X,Yin C,Tu Q,Shen X,Bai W,Wang Q,Tao Y,Yin H

Fri May 01 00:00:00 UTC 2020

Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.

Ecotoxicology and environmental safety

Luo Y,Peng J,Huang C,Cao Y

Sat Aug 01 00:00:00 UTC 2020

Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.

Frontiers in pharmacology

Li T,Fang T,Xu L,Liu X,Li X,Xue M,Yu X,Sun B,Chen L

Wed Feb 10 00:00:00 UTC 2021

Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.

Frontiers in pharmacology

Li T,Fang T,Xu L,Liu X,Li X,Xue M,Yu X,Sun B,Chen L

Wed Feb 10 00:00:00 UTC 2021

Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.

Frontiers in pharmacology

Li T,Fang T,Xu L,Liu X,Li X,Xue M,Yu X,Sun B,Chen L

Wed Feb 10 00:00:00 UTC 2021

Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Xia B,Yu J,He T,Liu X,Su J,Wang M,Wang J,Zhu Y

Sat Feb 01 00:00:00 UTC 2020

Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.

Cellular signalling

Liu AP,Yuan QH,Zhang B,Yang L,He QW,Chen K,Liu QS,Li Z,Zhan J

Fri May 01 00:00:00 UTC 2020

The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.

OncoTargets and therapy

Shang Y,Wang Q,Li J,Zhao Q,Huang X,Dong H,Liu H,Zhang Y,Zhang J,Gui R,Nie X

Tue Apr 12 00:00:00 UTC 2022

The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.

Nutrients

Liu Y,Fan D

Sat Jan 18 00:00:00 UTC 2020

Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.

Veterinary research

Chu B,Zhu Y,Su J,Xia B,Zou Y,Nie J,Zhang W,Wang J

Wed Aug 05 00:00:00 UTC 2020

N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.

International journal of molecular medicine

Liu X,Wu Y,Zhou D,Xie Y,Zhou Y,Lu Y,Yang R,Liu S

Sun Nov 01 00:00:00 UTC 2020

N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.

International journal of molecular medicine

Liu X,Wu Y,Zhou D,Xie Y,Zhou Y,Lu Y,Yang R,Liu S

Sun Nov 01 00:00:00 UTC 2020

ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.

International journal of oncology

Wang L,Tan Z,Zhang Y,Kady Keita N,Liu H,Zhang Y

Fri May 01 00:00:00 UTC 2020

Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.

The Journal of clinical investigation

Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H

Wed Jan 02 00:00:00 UTC 2019

Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.

The Journal of clinical investigation

Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H

Wed Jan 02 00:00:00 UTC 2019

Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.

Archives of toxicology

Zhao Q,Niu Q,Chen J,Xia T,Zhou G,Li P,Dong L,Xu C,Tian Z,Luo C,Liu L,Zhang S,Wang A

Fri Mar 01 00:00:00 UTC 2019

Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.

Archives of toxicology

Zhao Q,Niu Q,Chen J,Xia T,Zhou G,Li P,Dong L,Xu C,Tian Z,Luo C,Liu L,Zhang S,Wang A

Fri Mar 01 00:00:00 UTC 2019

Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.

Frontiers in pharmacology

Wang D,Guo H,Yang H,Wang D,Gao P,Wei W

Tue Sep 29 00:00:00 UTC 2020

Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.

Toxicology and applied pharmacology

Zhou G,Tang S,Yang L,Niu Q,Chen J,Xia T,Wang S,Wang M,Zhao Q,Liu L,Li P,Dong L,Yang K,Zhang S,Wang A

Sun Sep 01 00:00:00 UTC 2019

Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.

Breast cancer (Tokyo, Japan)

Cheng X,Tan S,Duan F,Yuan Q,Li Q,Deng G

Fri Nov 01 00:00:00 UTC 2019

Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)₂D₃ on the osteoclastogenesis.

Biochemical and biophysical research communications

Ji L,Gao J,Kong R,Gao Y,Ji X,Zhao D

Tue Apr 16 00:00:00 UTC 2019

Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.

Biochemical pharmacology

Liu Y,Fan D

Tue Oct 01 00:00:00 UTC 2019

Repression of MicroRNA-30e by Hepatitis C Virus Enhances Fatty Acid Synthesis.

Hepatology communications

Sasaki R,Sur S,Cheng Q,Steele R,Ray RB

Mon Jul 01 00:00:00 UTC 2019

Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.

Journal of cellular physiology

Pan Y,Li Z,Wang Y,Yan M,Wu J,Beharee RG,Yu J

Sun Sep 01 00:00:00 UTC 2019

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.

Cell death & disease

Ni Z,Kuang L,Chen H,Xie Y,Zhang B,Ouyang J,Wu J,Zhou S,Chen L,Su N,Tan Q,Luo X,Chen B,Chen S,Yin L,Huang H,Du X,Chen L

Mon Jul 08 00:00:00 UTC 2019

Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.

Journal of cellular physiology

Li R,Du J,Yao Y,Yao G,Wang X

Fri Nov 01 00:00:00 UTC 2019

Hypothermic oxygenated machine perfusion alleviates liver injury in donation after circulatory death through activating autophagy in mice.

Artificial organs

Zeng X,Wang S,Li S,Yang Y,Fang Z,Huang H,Wang Y,Fan X,Ye Q

Sun Dec 01 00:00:00 UTC 2019

Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells.

International journal of ophthalmology

Li R,Du JH,Yao GM,Yao Y,Zhang J

Thu Oct 01 00:00:00 UTC 2020

Homocysteine induces human mesangial cell apoptosis via the involvement of autophagy and endoplasmic reticulum stress.

RSC advances

Liang S,Liu H,Liu S,Wei M,Gao F,Xue J,Sun L,Wang M,Jiang H,Chen L

Tue Oct 01 00:00:00 UTC 2019

The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.

PloS one

Liu H,Zhao J,Fu R,Zhu C,Fan D

Fri Jan 24 00:00:00 UTC 2020

Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.

Oxidative medicine and cellular longevity

Li Y,Wu Y,Jiang K,Han W,Zhang J,Xie L,Liu Y,Xiao J,Wang X

Thu Jun 25 00:00:00 UTC 2020

Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.

Biological & pharmaceutical bulletin

Inamura A,Muraoka-Hirayama S,Sakurai K

Thu Apr 09 00:00:00 UTC 2020

Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.

Biological & pharmaceutical bulletin

Inamura A,Muraoka-Hirayama S,Sakurai K

Thu Apr 09 00:00:00 UTC 2020

LncRNA expression profile during autophagy and Malat1 function in macrophages.

PloS one

Ma Z,Zhang J,Xu X,Qu Y,Dong H,Dang J,Huo Z,Xu G

Thu Apr 02 00:00:00 UTC 2020

Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.

Molecular psychiatry

Sharoar MG,Hu X,Ma XM,Zhu X,Yan R

Sun Sep 01 00:00:00 UTC 2019

Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1.

Aging

Cheng FY,Lee YH,Hsu YH,Chiu IJ,Chiu YJ,Lin YF,Chiu HW

Tue Nov 12 00:00:00 UTC 2019

Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.

Frontiers in immunology

Li C,Liu J,Zhang X,Wei S,Huang X,Huang Y,Wei J,Qin Q

Wed Sep 09 00:00:00 UTC 2020

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.

Molecular cancer

Cai Q,Wang S,Jin L,Weng M,Zhou D,Wang J,Tang Z,Quan Z

Fri Apr 05 00:00:00 UTC 2019

RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.

Cell death and differentiation

Sheng Y,Song Y,Li Z,Wang Y,Lin H,Cheng H,Zhou R

Tue May 01 00:00:00 UTC 2018

RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.

Cell death and differentiation

Sheng Y,Song Y,Li Z,Wang Y,Lin H,Cheng H,Zhou R

Tue May 01 00:00:00 UTC 2018

RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.

Cell death and differentiation

Sheng Y,Song Y,Li Z,Wang Y,Lin H,Cheng H,Zhou R

Tue May 01 00:00:00 UTC 2018

RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.

Cell death and differentiation

Sheng Y,Song Y,Li Z,Wang Y,Lin H,Cheng H,Zhou R

Tue May 01 00:00:00 UTC 2018

Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.

Aging cell

Ji J,Xue TF,Guo XD,Yang J,Guo RB,Wang J,Huang JY,Zhao XJ,Sun XL

Wed Aug 01 00:00:00 UTC 2018

Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.

Aging cell

Ji J,Xue TF,Guo XD,Yang J,Guo RB,Wang J,Huang JY,Zhao XJ,Sun XL

Wed Aug 01 00:00:00 UTC 2018

CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.

Cancer letters

Hu X,Mei S,Meng W,Xue S,Jiang L,Yang Y,Hui L,Chen Y,Guan MX

Sun Jul 01 00:00:00 UTC 2018

CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.

Cancer letters

Hu X,Mei S,Meng W,Xue S,Jiang L,Yang Y,Hui L,Chen Y,Guan MX

Sun Jul 01 00:00:00 UTC 2018

Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.

Frontiers in immunology

Chen D,Feng C,Tian X,Zheng N,Wu Z

Fri Aug 16 00:00:00 UTC 2019

Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.

Frontiers in immunology

Chen D,Feng C,Tian X,Zheng N,Wu Z

Fri Aug 16 00:00:00 UTC 2019

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils.

Frontiers in immunology

Iula L,Keitelman IA,Sabbione F,Fuentes F,Guzman M,Galletti JG,Gerber PP,Ostrowski M,Geffner JR,Jancic CC,Trevani AS

Mon Apr 08 00:00:00 UTC 2019

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils.

Frontiers in immunology

Iula L,Keitelman IA,Sabbione F,Fuentes F,Guzman M,Galletti JG,Gerber PP,Ostrowski M,Geffner JR,Jancic CC,Trevani AS

Mon Apr 08 00:00:00 UTC 2019

The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Cai T,Zhang C,Zhao Z,Li S,Cai H,Chen X,Cai D,Liu W,Yan Y,Xie K,Pan H,Zeng X

Wed Aug 01 00:00:00 UTC 2018

The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Cai T,Zhang C,Zhao Z,Li S,Cai H,Chen X,Cai D,Liu W,Yan Y,Xie K,Pan H,Zeng X

Wed Aug 01 00:00:00 UTC 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 UTC 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 UTC 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 UTC 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 UTC 2018

Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.

Neuropharmacology

Li C,Zhang J,Xu H,Chang M,Lv C,Xue W,Song Z,Zhang L,Zhang X,Tian X

Fri Jun 01 00:00:00 UTC 2018

Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.

Neuropharmacology

Li C,Zhang J,Xu H,Chang M,Lv C,Xue W,Song Z,Zhang L,Zhang X,Tian X

Fri Jun 01 00:00:00 UTC 2018

Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.

Journal of applied toxicology : JAT

Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S

Sat Sep 01 00:00:00 UTC 2018

Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.

Journal of applied toxicology : JAT

Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S

Sat Sep 01 00:00:00 UTC 2018

Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia.

International journal of ophthalmology

Li R,Wang LZ,Du JH,Zhao L,Yao Y

Thu Oct 01 00:00:00 UTC 2020

Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia.

International journal of ophthalmology

Li R,Wang LZ,Du JH,Zhao L,Yao Y

Thu Oct 01 00:00:00 UTC 2020

LP1 from Lentinula edodes C_91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.

International journal of molecular sciences

Batool S,Joseph TP,Hussain M,Vuai MS,Khinsar KH,Din SRU,Padhiar AA,Zhong M,Ning A,Zhang W,Cao J,Huang M

Sun Sep 30 00:00:00 UTC 2018

LP1 from Lentinula edodes C_91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.

International journal of molecular sciences

Batool S,Joseph TP,Hussain M,Vuai MS,Khinsar KH,Din SRU,Padhiar AA,Zhong M,Ning A,Zhang W,Cao J,Huang M

Sun Sep 30 00:00:00 UTC 2018

MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang N,Yang L,Zhang H,Lu X,Wang J,Cao Y,Chen L,Wang X,Cong L,Li J,Wang N,Liu Z,Wang L

Fri Mar 16 00:00:00 UTC 2018

MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang N,Yang L,Zhang H,Lu X,Wang J,Cao Y,Chen L,Wang X,Cong L,Li J,Wang N,Liu Z,Wang L

Fri Mar 16 00:00:00 UTC 2018

MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang N,Yang L,Zhang H,Lu X,Wang J,Cao Y,Chen L,Wang X,Cong L,Li J,Wang N,Liu Z,Wang L

Fri Mar 16 00:00:00 UTC 2018

MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang N,Yang L,Zhang H,Lu X,Wang J,Cao Y,Chen L,Wang X,Cong L,Li J,Wang N,Liu Z,Wang L

Fri Mar 16 00:00:00 UTC 2018

7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.

Marine drugs

Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH

Mon Mar 26 00:00:00 UTC 2018

7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.

Marine drugs

Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH

Mon Mar 26 00:00:00 UTC 2018

ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.

Diabetes

Xiao Y,Deng Y,Yuan F,Xia T,Liu H,Li Z,Liu Z,Ying H,Liu Y,Zhai Q,Chen S,Guo F

Mon May 01 00:00:00 UTC 2017

ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.

Diabetes

Xiao Y,Deng Y,Yuan F,Xia T,Liu H,Li Z,Liu Z,Ying H,Liu Y,Zhai Q,Chen S,Guo F

Mon May 01 00:00:00 UTC 2017

7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.

Life sciences

Wang EX,Zou BY,Shi L,Du LY,Zhu YY,Jiang YM,Ma XD,Kang XH,Wang CY,Zhen YH,Sun LD

Sat Jul 01 00:00:00 UTC 2017

7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.

Life sciences

Wang EX,Zou BY,Shi L,Du LY,Zhu YY,Jiang YM,Ma XD,Kang XH,Wang CY,Zhen YH,Sun LD

Sat Jul 01 00:00:00 UTC 2017

Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.

Journal of agricultural and food chemistry

Zhang J,Zhu Y,Shi Y,Han Y,Liang C,Feng Z,Zheng H,Eng M,Wang J

Wed Oct 11 00:00:00 UTC 2017

Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.

Journal of agricultural and food chemistry

Zhang J,Zhu Y,Shi Y,Han Y,Liang C,Feng Z,Zheng H,Eng M,Wang J

Wed Oct 11 00:00:00 UTC 2017

Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.

Journal of endodontics

Cheng X,Zhu L,Zhang J,Yu J,Liu S,Lv F,Lin Y,Liu G,Peng B

Mon May 01 00:00:00 UTC 2017

Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.

Journal of endodontics

Cheng X,Zhu L,Zhang J,Yu J,Liu S,Lv F,Lin Y,Liu G,Peng B

Mon May 01 00:00:00 UTC 2017

Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.

The Biochemical journal

Du C,Zhang T,Xiao X,Shi Y,Duan H,Ren Y

Wed Aug 02 00:00:00 UTC 2017

Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.

The Biochemical journal

Du C,Zhang T,Xiao X,Shi Y,Duan H,Ren Y

Wed Aug 02 00:00:00 UTC 2017

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.

Nature communications

Liu M,Liang K,Zhen J,Zhou M,Wang X,Wang Z,Wei X,Zhang Y,Sun Y,Zhou Z,Su H,Zhang C,Li N,Gao C,Peng J,Yi F

Mon Sep 04 00:00:00 UTC 2017

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.

Nature communications

Liu M,Liang K,Zhen J,Zhou M,Wang X,Wang Z,Wei X,Zhang Y,Sun Y,Zhou Z,Su H,Zhang C,Li N,Gao C,Peng J,Yi F

Mon Sep 04 00:00:00 UTC 2017

TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.

Scientific reports

Li W,Yang X,Zheng T,Xing S,Wu Y,Bian F,Wu G,Li Y,Li J,Bai X,Wu D,Jia X,Wang L,Zhu L,Jin S

Fri Mar 17 00:00:00 UTC 2017

TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.

Scientific reports

Li W,Yang X,Zheng T,Xing S,Wu Y,Bian F,Wu G,Li Y,Li J,Bai X,Wu D,Jia X,Wang L,Zhu L,Jin S

Fri Mar 17 00:00:00 UTC 2017

SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.

Oncotarget

Wang M,Wu H,Li S,Xu Z,Li X,Yang Y,Li B,Li Y,Guo J,Chen H

Fri Oct 27 00:00:00 UTC 2017

SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.

Oncotarget

Wang M,Wu H,Li S,Xu Z,Li X,Yang Y,Li B,Li Y,Guo J,Chen H

Fri Oct 27 00:00:00 UTC 2017

SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.

Oncotarget

Wang M,Wu H,Li S,Xu Z,Li X,Yang Y,Li B,Li Y,Guo J,Chen H

Fri Oct 27 00:00:00 UTC 2017

miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.

Cell death and differentiation

Wang Y,Zhang X,Tang W,Lin Z,Xu L,Dong R,Li Y,Li J,Zhang Z,Li X,Zhao L,Wei JJ,Shao C,Kong B,Liu Z

Fri Dec 01 00:00:00 UTC 2017

Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.

Biomaterials

Sun R,Shen S,Zhang YJ,Xu CF,Cao ZT,Wen LP,Wang J

Sat Oct 01 00:00:00 UTC 2016

Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.

Biomaterials

Sun R,Shen S,Zhang YJ,Xu CF,Cao ZT,Wen LP,Wang J

Sat Oct 01 00:00:00 UTC 2016

Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.

Nanoscale

Jin P,Wei P,Zhang Y,Lin J,Sha R,Hu Y,Zhang J,Zhou W,Yao H,Ren L,Yang JY,Liu Y,Wen L

Thu Nov 10 00:00:00 UTC 2016

Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.

Nanoscale

Jin P,Wei P,Zhang Y,Lin J,Sha R,Hu Y,Zhang J,Zhou W,Yao H,Ren L,Yang JY,Liu Y,Wen L

Thu Nov 10 00:00:00 UTC 2016

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.

Biochemical pharmacology

Liu S,Zhu L,Zhang J,Yu J,Cheng X,Peng B

Fri Apr 15 00:00:00 UTC 2016

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.

Biochemical pharmacology

Liu S,Zhu L,Zhang J,Yu J,Cheng X,Peng B

Fri Apr 15 00:00:00 UTC 2016

Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Li S,Zhou A,Wang J,Zhang S

Fri Apr 01 00:00:00 UTC 2016

Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Li S,Zhou A,Wang J,Zhang S

Fri Apr 01 00:00:00 UTC 2016

Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.

Chemical research in toxicology

Shi Q,Song X,Liu Z,Wang Y,Wang Y,Fu J,Su C,Xia X,Song E,Song Y

Mon Jul 18 00:00:00 UTC 2016

Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.

Chemical research in toxicology

Shi Q,Song X,Liu Z,Wang Y,Wang Y,Fu J,Su C,Xia X,Song E,Song Y

Mon Jul 18 00:00:00 UTC 2016

Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.

Frontiers in cellular neuroscience

Chen J,Liu L,Liu Y,Liu X,Qu C,Meng F,Ma J,Lin Y,Xue Y

Tue May 31 00:00:00 UTC 2016

Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.

Frontiers in cellular neuroscience

Chen J,Liu L,Liu Y,Liu X,Qu C,Meng F,Ma J,Lin Y,Xue Y

Tue May 31 00:00:00 UTC 2016

Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors.

BMC cancer

Wang C,Ma Y,Hu Q,Xie T,Wu J,Zeng F,Song F

Wed Jul 27 00:00:00 UTC 2016

Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors.

BMC cancer

Wang C,Ma Y,Hu Q,Xie T,Wu J,Zeng F,Song F

Wed Jul 27 00:00:00 UTC 2016

Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.

Biomaterials

Wei PF,Jin PP,Barui AK,Hu Y,Zhang L,Zhang JQ,Shi SS,Zhang HR,Lin J,Zhou W,Zhang YJ,Ruan RQ,Patra CR,Wen LP

Tue Dec 01 00:00:00 UTC 2015

Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.

Biomaterials

Wei PF,Jin PP,Barui AK,Hu Y,Zhang L,Zhang JQ,Shi SS,Zhang HR,Lin J,Zhou W,Zhang YJ,Ruan RQ,Patra CR,Wen LP

Tue Dec 01 00:00:00 UTC 2015

Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells.

Autophagy

Yoo BH,Zagryazhskaya A,Li Y,Koomson A,Khan IA,Sasazuki T,Shirasawa S,Rosen KV

Mon Jun 20 00:00:00 UTC 2016

Autophagy

Yoo BH,Zagryazhskaya A,Li Y,Koomson A,Khan IA,Sasazuki T,Shirasawa S,Rosen KV

Mon Jun 20 00:00:00 UTC 2016

Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells.

Microbes and infection

Liu E,Van Grol J,Subauste CS

Wed Apr 01 00:00:00 UTC 2015

Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells.

Microbes and infection

Liu E,Van Grol J,Subauste CS

Wed Apr 01 00:00:00 UTC 2015

Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.

Journal of cellular and molecular medicine

Zhu X,Ruan Z,Yang X,Chu K,Wu H,Li Y,Huang Y

Thu Jan 01 00:00:00 UTC 2015

Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.

Journal of cellular and molecular medicine

Zhu X,Ruan Z,Yang X,Chu K,Wu H,Li Y,Huang Y

Thu Jan 01 00:00:00 UTC 2015

Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.

Experimental cell research

Yuan X,Du J,Hua S,Zhang H,Gu C,Wang J,Yang L,Huang J,Yu J,Liu F

Thu Jan 15 00:00:00 UTC 2015

Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.

Experimental cell research

Yuan X,Du J,Hua S,Zhang H,Gu C,Wang J,Yang L,Huang J,Yu J,Liu F

Thu Jan 15 00:00:00 UTC 2015

Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer.

Biochemical and biophysical research communications

Wang L,Yao L,Zheng YZ,Xu Q,Liu XP,Hu X,Wang P,Shao ZM

Fri Mar 20 00:00:00 UTC 2015

Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer.

Biochemical and biophysical research communications

Wang L,Yao L,Zheng YZ,Xu Q,Liu XP,Hu X,Wang P,Shao ZM

Fri Mar 20 00:00:00 UTC 2015

Potent effects of dioscin against obesity in mice.

Scientific reports

Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J

Thu Jan 22 00:00:00 UTC 2015

Potent effects of dioscin against obesity in mice.

Scientific reports

Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J

Thu Jan 22 00:00:00 UTC 2015

Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.

Molecules (Basel, Switzerland)

Dong D,Xu L,Han X,Qi Y,Xu Y,Yin L,Liu K,Peng J

Fri May 30 00:00:00 UTC 2014

Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.

Molecular cell

Lu Y,Zhang Z,Sun D,Sweeney ST,Gao FB

Thu Oct 24 00:00:00 UTC 2013

Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.

Molecular cell

Lu Y,Zhang Z,Sun D,Sweeney ST,Gao FB

Thu Oct 24 00:00:00 UTC 2013

Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.

PloS one

Jin R,Zhu W,Cao S,Chen R,Jin H,Liu Y,Wang S,Wang W,Xiao G

Thu Aug 15 00:00:00 UTC 2013

Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.

PloS one

Jin R,Zhu W,Cao S,Chen R,Jin H,Liu Y,Wang S,Wang W,Xiao G

Thu Aug 15 00:00:00 UTC 2013

Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.

PloS one

Jin R,Zhu W,Cao S,Chen R,Jin H,Liu Y,Wang S,Wang W,Xiao G

Thu Aug 15 00:00:00 UTC 2013

Piperlongumine induces autophagy by targeting p38 signaling.

Cell death & disease

Wang Y,Wang JW,Xiao X,Shan Y,Xue B,Jiang G,He Q,Chen J,Xu HG,Zhao RX,Werle KD,Cui R,Liang J,Li YL,Xu ZX

Thu Oct 03 00:00:00 UTC 2013

Piperlongumine induces autophagy by targeting p38 signaling.

Cell death & disease

Wang Y,Wang JW,Xiao X,Shan Y,Xue B,Jiang G,He Q,Chen J,Xu HG,Zhao RX,Werle KD,Cui R,Liang J,Li YL,Xu ZX

Thu Oct 03 00:00:00 UTC 2013

P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.

Free radical biology & medicine

Zhan Y,Gong K,Chen C,Wang H,Li W

Wed Aug 01 00:00:00 UTC 2012

P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.

Free radical biology & medicine

Zhan Y,Gong K,Chen C,Wang H,Li W

Wed Aug 01 00:00:00 UTC 2012

Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.

Journal of virology

Li J,Liu Y,Wang Z,Liu K,Wang Y,Liu J,Ding H,Yuan Z

Fri Jul 01 00:00:00 UTC 2011

Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.

Journal of virology

Li J,Liu Y,Wang Z,Liu K,Wang Y,Liu J,Ding H,Yuan Z

Fri Jul 01 00:00:00 UTC 2011

The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels.

PloS one

Portillo JA,Okenka G,Reed E,Subauste A,Van Grol J,Gentil K,Komatsu M,Tanaka K,Landreth G,Levine B,Subauste CS

Fri Dec 31 00:00:00 UTC 2010

The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels.

PloS one

Portillo JA,Okenka G,Reed E,Subauste A,Van Grol J,Gentil K,Komatsu M,Tanaka K,Landreth G,Levine B,Subauste CS

Fri Dec 31 00:00:00 UTC 2010

Autophagy is essential for mitochondrial clearance in mature T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950)

Pua HH,Guo J,Komatsu M,He YW

Wed Apr 01 00:00:00 UTC 2009

Autophagy is essential for mitochondrial clearance in mature T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950)

Pua HH,Guo J,Komatsu M,He YW

Wed Apr 01 00:00:00 UTC 2009

A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.

Cell death and differentiation

Xu ZX,Liang J,Haridas V,Gaikwad A,Connolly FP,Mills GB,Gutterman JU

Thu Nov 01 00:00:00 UTC 2007

A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.

Cell death and differentiation

Xu ZX,Liang J,Haridas V,Gaikwad A,Connolly FP,Mills GB,Gutterman JU

Thu Nov 01 00:00:00 UTC 2007

Bioinformatics

Protein Aliases: APG 5; APG5 autophagy 5 like (APG5L); APG5-like; Apoptosis-specific protein; Apoptosis-specific protein (ASP); ATG5 autophagy related 5 homolog; Autophagy protein 5; autophagy-related 5

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Gene Aliases: 2010107M05Rik; 3110067M24Rik; APG5; APG5-LIKE; APG5L; ASP; ATG5; Atg5l; AW319544; C88337; hAPG5; Paddy

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UniProt ID: (Human) Q9H1Y0, (Mouse) Q99J83

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Entrez Gene ID: (Human) 9474, (Mouse) 11793, (Rat) 365601

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Function(s)

protein binding Atg8 ligase activity membrane trafficking regulatory protein

Process(es)

autophagosome assembly mitophagy blood vessel remodeling regulation of cytokine secretion involved in immune response C-terminal protein lipidation autophagy apoptotic process cellular response to nitrogen starvation response to fungus macroautophagy cellular homeostasis antigen processing and presentation of endogenous antigen negative regulation of protein ubiquitination aggrephagy negative stranded viral RNA replication vasodilation response to drug negative regulation of apoptotic process post-translational protein modification nucleophagy negative thymic T cell selection innate immune response otolith development regulation of release of sequestered calcium ion into cytosol ventricular cardiac muscle cell development heart contraction negative regulation of cell death protein lipidation involved in autophagosome assembly positive regulation of mucus secretion regulation of cilium assembly positive regulation of mitophagy negative regulation of reactive oxygen species metabolic process negative regulation of histone H4-K16 acetylation immune system process regulation of reactive oxygen species metabolic process

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ATG5 Polyclonal Antibody

ATG5 Antibody (10181-2-AP) in ICC/IF

Product Details

10181-2-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

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Type

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