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          • Primary Antibodies ›
          • Cytokeratin 19 Antibodies

          Bioss

          Cytokeratin 19 Monoclonal Antibody (10H7), Alexa Fluor™ 680

          View all (170) Cytokeratin 19 antibodies

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          Cite Cytokeratin 19 Monoclonal Antibody (10H7), Alexa Fluor™ 680

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          Cytokeratin 19 Monoclonal Antibody (10H7), Alexa Fluor™ 680

          Product Details

          BSM-33057M-A680

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-5,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG

          Class

          Monoclonal

          Type

          Antibody

          Clone

          10H7

          Immunogen

          KLH conjugated synthetic peptide derived from human Cytokeratin 19
          3D Epitope / Immunogen

          Conjugate

          Alexa Fluor™ 680 Alexa Fluor™ 680 Alexa Fluor™ 680
          • Unconjugated
          • Alexa Fluor 350 
          • Alexa Fluor 750 
          • Biotin 
          • Cyanine3
          • Cyanine5 
          • Cyanine5.5 
          • Cyanine7
          • FITC
          • HRP
          • Request custom conjugation

          Excitation/Emission Max

          681/704 nm View spectra spectra

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein G

          Storage buffer

          TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 40-kDa keratin intermediate filament; C K1CS; CK 19; CK-19; cytokeratin 19; Cytokeratin-19; K19; keratin 19, type I; keratin complex 1, acidic, gene 19; Keratin, type I cytoskeletal 19; keratin, type I, 40-kd; Keratin-19; MGC15366; Type I keratin Ka19; unnamed protein product

          View more View less

          Gene Aliases: AI663979; CK19; EndoC; K19; K1CS; Ka19; Krt-1.19; Krt1-19; KRT19

          View more View less

          UniProt ID: (Human) P08727, (Mouse) P19001, (Rat) Q63279

          View more View less

          Entrez Gene ID: (Human) 3880, (Mouse) 16669, (Rat) 360626

          View more View less

          Function(s)
          structural molecule activity structural constituent of cytoskeleton protein binding structural constituent of muscle structural constituent of epidermis macromolecular complex binding protein complex binding
          Process(es)
          morphogenesis of an epithelium Notch signaling pathway epithelial cell differentiation response to estrogen intermediate filament organization sarcomere organization cell differentiation involved in embryonic placenta development
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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