Bax Monoclonal Antibody (3C1), FITC

protein binding lipid binding channel activity Hsp70 protein binding identical protein binding protein homodimerization activity protein heterodimerization activity chaperone binding BH3 domain binding heat shock protein binding macromolecular complex binding BH domain binding

B cell apoptotic process release of cytochrome c from mitochondria apoptotic process mitochondrial fusion extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage apoptotic mitochondrial changes response to toxic substance establishment or maintenance of transmembrane electrochemical gradient negative regulation of mitochondrial membrane potential positive regulation of protein complex assembly negative regulation of protein binding endoplasmic reticulum calcium ion homeostasis release of matrix enzymes from mitochondria cellular response to stress cellular response to unfolded protein regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process regulation of neuron apoptotic process positive regulation of neuron apoptotic process mitochondrial fragmentation involved in apoptotic process regulation of mitochondrial membrane potential intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of release of cytochrome c from mitochondria apoptotic signaling pathway extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway execution phase of apoptosis fibril organization cellular response to virus positive regulation of apoptotic DNA fragmentation regulation of intracellular signal transduction positive regulation of IRE1-mediated unfolded protein response B cell receptor apoptotic signaling pathway regulation of apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway ovarian follicle development response to hypoxia neuron migration leukocyte homeostasis T cell homeostatic proliferation B cell homeostasis kidney development blood vessel remodeling myeloid cell homeostasis B cell negative selection B cell homeostatic proliferation positive regulation of B cell apoptotic process response to ischemia glycosphingolipid metabolic process regulation of nitrogen utilization cellular response to DNA damage stimulus mitochondrion organization mitochondrial membrane organization inner mitochondrial membrane organization outer mitochondrial membrane organization germ cell development spermatogenesis nervous system development sex differentiation cell proliferation negative regulation of cell proliferation male gonad development response to xenobiotic stimulus fertilization response to wounding response to salt stress post-embryonic development response to ionizing radiation response to gamma radiation positive regulation of calcium ion transport into cytosol hypothalamus development cerebral cortex development negative regulation of endoplasmic reticulum calcium ion concentration negative regulation of peptidyl-serine phosphorylation regulation of mammary gland epithelial cell proliferation glial cell apoptotic process cellular response to UV limb morphogenesis ectopic germ cell programmed cell death swimming behavior response to cocaine odontogenesis of dentin-containing tooth negative regulation of neuron apoptotic process development of secondary sexual characteristics cellular respiration retinal cell programmed cell death response to copper ion positive regulation of developmental pigmentation negative regulation of fibroblast proliferation spermatid differentiation post-embryonic camera-type eye morphogenesis response to axon injury homeostasis of number of cells homeostasis of number of cells within a tissue protein insertion into mitochondrial membrane positive regulation of release of sequestered calcium ion into cytosol neuron apoptotic process response to corticosterone regulation of cell cycle Sertoli cell proliferation retina development in camera-type eye positive regulation of apoptotic process involved in mammary gland involution vagina development thymocyte apoptotic process cellular response to hydrogen peroxide intrinsic apoptotic signaling pathway by p53 class mediator response to anesthetic regulation of mitochondrial membrane permeability involved in apoptotic process positive regulation of mitochondrial membrane permeability involved in apoptotic process apoptotic process involved in patterning of blood vessels apoptotic process involved in embryonic digit morphogenesis regulation of mitochondrial membrane permeability involved in programmed necrotic cell death response to insulin-like growth factor stimulus negative regulation of apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway in absence of ligand