Product References
Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zohny SM,Habib MZ,Mohamad MI,Elayat WM,Elhossiny RM,El-Salam MFA,Hassan GAM,Aboul-Fotouh S
PA5-27094 was used in Immunohistochemistry to draw attention to the favorable cognitive effects of memantine/aripiprazole combination in autistic subjects which could be mediated via enhancing CREB/BDNF signaling with increased expression of astrocytic Glt-1 and restoration of GABA/glutamate balance, leading to inhibition of hippocampal NFTs formation and neuronal apoptosis.
Wed Mar 01 00:00:00 EST 2023
A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model.
Antioxidants (Basel, Switzerland)
Shahin NN,Shamma RN,Ahmed IS
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Immunohistochemistry
Sun Aug 07 00:00:00 EDT 2022
Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway.
Translational andrology and urology
Su Y,Xu J,Chen S,Feng J,Li J,Lei Z,Qiao L,Wang Y,Zeng D
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Western Blot
Mon Aug 01 00:00:00 EDT 2022
Infarct-preconditioning exosomes of umbilical cord mesenchymal stem cells promoted vascular remodeling and neurological recovery after stroke in rats.
Stem cell research & therapy
Ye YC,Chang ZH,Wang P,Wang YW,Liang J,Chen C,Wang JJ,Sun HT,Wang Y,Li XH
PA5-27094 was used in Western Blotting to investigate if exosomes secreted in response to infarction microenvironment could have further therapeutic effects.
Thu Jul 28 00:00:00 EDT 2022
Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats.
Frontiers in nutrition
Long X,Wu H,Zhou Y,Wan Y,Kan X,Gong J,Zhao X
PA5-27094 was used in Western Blotting to show that L. fermentum SCHY34 showed a great biological scavenging and potential effect on alleviating the toxicity of lead ions.
Sat Jul 16 00:00:00 EDT 2022
Necrostatin-1 mitigates renal ischaemia-reperfusion injury - time dependent - via aborting the interacting protein kinase (RIPK-1)-induced inflammatory immune response.
Clinical and experimental pharmacology & physiology
Ashour H,Hashem HA,Khowailed AA,Rashed LA,Hassan RM,Soliman AS
PA5-27094 was used in Western Blotting to show that RIPK1 inhibition ameliorates the inflammatory immune response induced by renal IRI.
Fri Apr 01 00:00:00 EDT 2022
Orientin, a Bio-Flavonoid from Trigonella hamosa L., Regulates COX-2/PGE-2 in A549 Cell Lines via miR-26b and miR-146a.
Pharmaceuticals (Basel, Switzerland)
Khalil HE,Ibrahim HM,Ahmed EA,Emeka PM,Alhaider IA
PA5-27094 was used in Western Blot to explore the potential role of Trigonella hamosa in regulating COX-2 mediated A549 non-small lung cancer progression.
Thu Jan 27 00:00:00 EST 2022
Human urine-derived stem cells protect against renal ischemia/reperfusion injury in a rat model via exosomal miR-146a-5p which targets IRAK1.
Theranostics
Li X,Liao J,Su X,Li W,Bi Z,Wang J,Su Q,Huang H,Wei Y,Gao Y,Li J,Liu L,Wang C
PA5-27094 was used in Western Blotting to study the protective effects of human urine-derived stem cells against a rat model of renal ischemia/reperfusion injury.
Tue Jun 01 00:00:00 EDT 2021
Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways.
International journal of molecular sciences
Alzahrani AM,Rajendran P,Veeraraghavan VP,Hanieh H
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Western Blot
Tue Mar 23 00:00:00 EDT 2021
Date Palm Pollen Extract Avert Doxorubicin-Induced Cardiomyopathy Fibrosis and Associated Oxidative/Nitrosative Stress, Inflammatory Cascade, and Apoptosis-Targeting Bax/Bcl-2 and Caspase-3 Signaling Pathways.
Animals : an open access journal from MDPI
Elblehi SS,El-Sayed YS,Soliman MM,Shukry M
PA5-27094 was used in Immunohistochemistry (Paraffin) to show that pre-coadministration of date palm pollen ethanolic extract partially mitigated doxorubicin-induced cardiac injuries via its antioxidant, anti-inflammatory, anti-fibrotic, and anti-apoptotic potential.
Sat Mar 20 00:00:00 EDT 2021
Date Palm Pollen Extract Avert Doxorubicin-Induced Cardiomyopathy Fibrosis and Associated Oxidative/Nitrosative Stress, Inflammatory Cascade, and Apoptosis-Targeting Bax/Bcl-2 and Caspase-3 Signaling Pathways.
Animals : an open access journal from MDPI
Elblehi SS,El-Sayed YS,Soliman MM,Shukry M
PA5-27094 was used in Immunohistochemistry (Paraffin) to show that pre-coadministration of date palm pollen ethanolic extract partially mitigated doxorubicin-induced cardiac injuries via its antioxidant, anti-inflammatory, anti-fibrotic, and anti-apoptotic potential.
Sat Mar 20 00:00:00 EDT 2021
Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies.
International journal of molecular sciences
Rajendran P,Ammar RB,Al-Saeedi FJ,Mohamed ME,ElNaggar MA,Al-Ramadan SY,Bekhet GM,Soliman AM
PA5-27094 was used in Western Blotting to demonstrate that kaempferol possesses notable hepatoprotective roles against zearalenone-induced damage, potentially through the stimulation of Nrf2/HO-1 cascades and PI3K/Akt signalling.
Mon Dec 28 00:00:00 EST 2020
Human umbilical cord-derived mesenchymal stem cells and human cord blood mononuclear cells protect against cisplatin-induced acute kidney injury in rat models.
Experimental and therapeutic medicine
Xu Q,Yan P,Duan XJ,Wu X,Chen XJ,Luo M,Peng JC,Feng LX,Liu J,Zhong HL,Cheng W,Zou QY,Duan SB
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Western Blot
Tue Dec 01 00:00:00 EST 2020
An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening.
ACS pharmacology & translational science
Kinarivala N,Morsy A,Patel R,Carmona AV,Sajib MS,Raut S,Mikelis CM,Al-Ahmad A,Trippier PC
PA5-27094 was used in Western Blot to report the characterization of the first CLN3 patient-specific induced pluripotent stem cell (iPSC)-derived model of the blood-brain barrier and establish the suitability of an iPSC-derived neuron model of the disease to facilitate compound screening.
Fri Oct 09 00:00:00 EDT 2020
Molecular mechanisms underlying histological and biochemical changes induced by nitrate in rat liver and the efficacy of S-Allylcysteine.
Ultrastructural pathology
Kattaia AA,Abd El-Baset SA,Mohamed EM,Abdul-Maksou RS,Elfakharany YM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Immunohistochemistry
Tue Jun 06 00:00:00 EDT 2017
Molecular mechanisms underlying histological and biochemical changes induced by nitrate in rat liver and the efficacy of S-Allylcysteine.
Ultrastructural pathology
Kattaia AA,Abd El-Baset SA,Mohamed EM,Abdul-Maksou RS,Elfakharany YM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Immunohistochemistry
Tue Jun 06 00:00:00 EDT 2017
Synergistic effects of cisplatin and proteasome inhibitor bortezomib on human bladder cancer cells.
Oncology letters
Konac E,Varol N,Kiliccioglu I,Bilen CY
Published figure using Bcl-2 polyclonal antibody (Product # PA5-27094) in Western Blot
Wed Jul 01 00:00:00 EDT 2015