Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CD132 Monoclonal Antibody (TUGm2), Biotin, eBioscience™
FIGURE: 1 / 1
CD132 Antibody (13-1321-82) in Flow
Staining of C57Bl/6 splenocytes with 1 µg of Rat IgG2b K Isotype Control Biotin (Product # 13-4031-82) (blue histogram) or 1 µg of Anti-Mouse CD132 Biotin (purple histogram) followed by Streptavidin PE (Product # 12-4317-87). Cells in the lymphocyte gate were used for analysis.
Product Details
13-1321-82
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2b, kappa
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
TUGm2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10736474
Product Specific Information
Description: This TUGm2 monoclonal antibody reacts with mouse CD132, which is also known as the common gamma chain. This 65-kDa subunit is shared by the IL-4, IL-7, IL-9, and IL-15 receptors. CD132 is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. Mutations in the human common gamma chain gene result in X-linked severe combined immunodeficiency (XSCID), a disease characterized by T cell deficiency leading to impairment of cell-mediated and humoral immunity.^M
^M
Applications Reported: This TUGm2 antibody has been reported for use in flow cytometric analysis.^M
^M
Applications Tested: This TUGm2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 2 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.^M
^M
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CD132; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL2R gamma; Interleukin-2 receptor subunit gamma; p64
Gene Aliases: [g]c; CD132; gamma(c); gc; Il2rg; p64
UniProt ID: (Mouse) P34902
Entrez Gene ID: (Mouse) 16186
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support