Product References
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Bioactive materials
Li S,Zhang L,Liu C,Kim J,Su K,Chen T,Zhao L,Lu X,Zhang H,Cui Y,Cui X,Yuan F,Pan H
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors.
Theranostics
Cao S,Hung YW,Wang YC,Chung Y,Qi Y,Ouyang C,Zhong X,Hu W,Coblentz A,Maghami E,Sun Z,Lin HH,Ann DK
12-2061-82 was used in Flow cytometry/Cell sorting to determine if attenuated host autophagy is sufficient to induce tumor rejection through reinforced adaptive immunity and whether dietary glutamine supplementation, mimicking attenuated host autophagy, is capable of promoting antitumor immunity.
Tue Aug 16 00:00:00 EDT 2022
Local and systemic inflammation triggers different outcomes of tumor growth related to infiltration of anti-tumor or pro-tumor macrophages.
Chinese medical journal
Liu X,Jiang Q,Shen S,Hou Y
12-2061-82 was used in Flow cytometry/Cell sorting to suggest that the different outcomes of tumor growth might be attributed to the infiltration of anti-tumor or pro-tumor immune cells, especially M1 or M2 type macrophages into tumor microenvironment.
Fri Aug 05 00:00:00 EDT 2022
L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis.
Journal of applied microbiology
Zhu Q,Zai H,Zhang K,Zhang X,Luo N,Li X,Hu Y,Wu Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2022
G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region.
Annals of translational medicine
Li Y,Li G,Zhang L,Li Y,Zhao Z
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.
Frontiers in pharmacology
Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sat Apr 02 00:00:00 EDT 2022
Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway.
International journal of medical sciences
Zhu X,Liu J,Pan H,Geng Z,Huang W,Liu T,Zhang B
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Immunocytochemistry
Tue Mar 15 00:00:00 EDT 2022
Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus.
Frontiers in immunology
Liu J,Zhang Y,Sheng H,Liang C,Liu H,Moran Guerrero JA,Lu Z,Mao W,Dai Z,Liu X,Zhang L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Cancer immunology research
Wu Q,Huang Q,Jiang Y,Sun F,Liang B,Wang J,Hu X,Sun M,Ma Z,Shi Y,Liang Y,Tan Y,Zeng D,Yao F,Xu X,Yao Z,Li S,Rong X,Huang N,Sun L,Liao W,Shi M
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Jan 20 00:00:00 EST 2022
Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics.
iScience
Nascimento Da Conceicao V,Sun Y,Ramachandran K,Chauhan A,Raveendran A,Venkatesan M,DeKumar B,Maity S,Vishnu N,Kotsakis GA,Worley PF,Gill DL,Mishra BB,Madesh M,Singh BB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Requirement of direct contact between chondrocytes and macrophages for the maturation of regenerative cartilage.
Scientific reports
Kanda K,Asawa Y,Inaki R,Fujihara Y,Hoshi K,Hikita A
12-2061-82 was used in Flow Cytometry to provide insights for establishing a method of in vitro cartilage regeneration.
Thu Nov 18 00:00:00 EST 2021
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Nov 15 00:00:00 EST 2021
PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway.
Frontiers in immunology
Kong F,Sun K,Zhu J,Li F,Lin F,Sun X,Luo X,Ren C,Lu L,Zhao S,Sun J,Wang Y,Shi J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
12-2061-82 was used in Flow Cytometry to demonstrate a new connection between the adipose tissue and the hypothalamus in obesity that contributes to neuroinflammation and hypothalamic pathologies.
Mon Jun 21 00:00:00 EDT 2021
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Cell death & disease
Zhang D,Huang J,Wang F,Ding H,Cui Y,Yang Y,Xu J,Luo H,Gao Y,Pan L,Wu Y,Gong Y,Xie L,Liu Z,Qu Y,Zhang L,Liu W,Zhang W,Zhao S,Yi Q,Niu T,Zheng Y
12-2061-82 was used in Flow Cytometry to demonstrate the role of the polycomb-group protein, BMI1, in the modulation of pro-myeloma macrophages.
Sat May 15 00:00:00 EDT 2021
Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis.
Stem cell research & therapy
Wang F,Kong L,Wang W,Shi L,Wang M,Chai Y,Xu J,Kang Q
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu May 13 00:00:00 EDT 2021
Azithromycin alleviates systemic lupus erythematosus via the promotion of M2 polarisation in lupus mice.
Cell death discovery
Wang J,Chen Q,Zhang Z,Wang S,Wang Y,Xiang M,Liang J,Xu J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Apr 16 00:00:00 EDT 2021
Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization.
Stem cell research & therapy
Dong B,Wang C,Zhang J,Zhang J,Gu Y,Guo X,Zuo X,Pan H,Hsu AC,Wang G,Wang F
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Wed Mar 24 00:00:00 EDT 2021
Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice.
Communications biology
Song L,Chang R,Sun X,Lu L,Gao H,Lu H,Lin R,Xu X,Liu Z,Zhan L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2021
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
12-2061 was used in Flow cytometry/Cell sorting to presents a multifunctional metal-phenolic nanoplatform for efficient X-ray mediated RT-RDT in combination with immunotherapy and may provide a new therapeutic option for cancer treatment.
Mon Feb 01 00:00:00 EST 2021
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Frontiers in pharmacology
Guo M,Xiao J,Sheng X,Zhang X,Tie Y,Wang L,Zhao L,Ji X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.
Nature communications
Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Jun 22 00:00:00 EDT 2020
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.
Nature communications
Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Jun 22 00:00:00 EDT 2020
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation.
JCI insight
Lee HJ,Ko JH,Kim HJ,Jeong HJ,Oh JY
12-2061 was used in Flow cytometry/Cell sorting to reveal that suppression of prostaglandin E2 (PGE2) and HGF secretion in MSCs by siRNA transfection partially reversed the effects of MSCs on MDSC differentiation.
Thu Jun 18 00:00:00 EDT 2020
Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress.
PloS one
Wan YM,Li ZQ,Liu C,He YF,Wang MJ,Wu XN,Zhang Y,Li YH
12-2061-82 was used in Flow Cytometry to investigate whether MSCs are effective in treating mice with alcoholic hepatitis (AH) and its underlying mechanism.
Thu May 07 00:00:00 EDT 2020
The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ.
Experimental & molecular medicine
Lee YS,Song SJ,Hong HK,Oh BY,Lee WY,Cho YB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ.
Experimental & molecular medicine
Lee YS,Song SJ,Hong HK,Oh BY,Lee WY,Cho YB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Macrophage polarization plays roles in bone formation instructed by calcium phosphate ceramics.
Journal of materials chemistry. B
Li M,Guo X,Qi W,Wu Z,de Bruijn JD,Xiao Y,Bao C,Yuan H
12-2061 was used in Flow cytometry/Cell sorting to investigate the roles of macrophages in material-instructed bone formation.
Wed Mar 04 00:00:00 EST 2020
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1.
Frontiers in endocrinology
Loiola RA,Wickstead ES,Solito E,McArthur S
12-2061-82 was used in Flow Cytometry to investigate the role of estrogen following brain tissue injury.
Tue Feb 25 00:00:00 EST 2020
Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.
Journal of neuroinflammation
Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
Rosiglitazone polarizes microglia and protects against pilocarpine-induced status epilepticus.
CNS neuroscience & therapeutics
Peng J,Wang K,Xiang W,Li Y,Hao Y,Guan Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.
Breast cancer research : BCR
Sabol RA,Bowles AC,Côté A,Wise R,O'Donnell B,Matossian MD,Hossain FM,Burks HE,Del Valle L,Miele L,Collins-Burow BM,Burow ME,Bunnell BA
12-2061 was used in Flow cytometry/Cell sorting to study the mechanisms by which obesity promotes tumour progression.
Wed May 22 00:00:00 EDT 2019
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.
Cancer immunology research
Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR
12-2061 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.
Mon Apr 01 00:00:00 EDT 2019
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
JCI insight
Gyori D,Lim EL,Grant FM,Spensberger D,Roychoudhuri R,Shuttleworth SJ,Okkenhaug K,Stephens LR,Hawkins PT
12-2061 was used in Flow cytometry/Cell sorting to study the role of CSF1R dependent TAMs on the immunosuppressive tumour microenvironment.
Thu Jun 07 00:00:00 EDT 2018
Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone.
Journal of neuroinflammation
Yin X,Feng L,Ma D,Yin P,Wang X,Hou S,Hao Y,Zhang J,Xin M,Feng J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Mar 27 00:00:00 EDT 2018
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Feb 17 00:00:00 EST 2017
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Feb 17 00:00:00 EST 2017