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Invitrogen
CD4 Monoclonal Antibody (RM4-5), PE
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FIGURE: 1 / 7
CD4 Antibody (MCD0404) in Flow
Stem cells international 2024 -
Effects of HucMSC-EVs on T lymphocyte subsets and Th1/Th2 ratio of splenocytes in NOD mice. The proportion of CD4 + T lymphocytes and Th1/Th2 ratio (IFN- gamma as a marker of Th1 cells, IL-4 as a marker of Th2 cells) was detected by flow cytometry: (a) HucMSC-EVs inhibited the proliferation of CD4 + T lymphocyte subsets; (b) HucMSC-EVs decreased the proportion of IFN- gamma ; and (c) HucMSC-EVs increased th... View More
Product Details
MCD0404
Applications
Tested Dilution
Publications
Product Specifications
Published species
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
RM4-5
Immunogen
Mouse CD4
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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