Product References
Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.
JCI insight
Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Feb 08 00:00:00 EST 2023
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Jan 30 00:00:00 EST 2023
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
Nature communications
McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sat Dec 10 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.
Biomolecules & therapeutics
Yoon H,Sung JH,Song MJ
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
15-0049 was used in Flow cytometry/Cell sorting to suggest that miR-21-5p may protect melanocytes via targeting STAT3 and regulating the regulatory T cell/effector T cell balance, providing a possible treatment for managing vitiligo.
Fri Jan 01 00:00:00 EST 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Fri Sep 10 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Cell
Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells.
International journal of nanomedicine
Tomić S,Ilić N,Kokol V,Gruden-Movsesijan A,Mihajlović D,Bekić M,Sofronić-Milosavljević L,Čolić M,Vučević D
15-0049 was used in Flow cytometry/Cell sorting to investigate how differentially functionalised cellulose nanofibrils affect dendritic cell properties, their viability, morphology, differentiation and maturation potential, and the capacity to regulate T cell-mediated immune response.
Mon Dec 31 00:00:00 EST 2018
The Synergistic Effects of the Glutathione Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against Mycobacterium tuberculosis.
Frontiers in immunology
Teskey G,Cao R,Islamoglu H,Medina A,Prasad C,Prasad R,Sathananthan A,Fraix M,Subbian S,Zhong L,Venketaraman V
15-0049 was used in Immunocytochemistry-immunoflourescence to examine if N-Acetyl Cysteine in combination with antibiotics would be sufficient to completely clear Mycobacterium tuberculosis infection within in vitro granulomas.
Mon Sep 30 00:00:00 EDT 2019
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.
Cell
Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Aug 10 00:00:00 EDT 2017
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.
Nature genetics
Reinius B,Mold JE,Ramsköld D,Deng Q,Johnsson P,Michaëlsson J,Frisén J,Sandberg R
15-0049 was used in Flow cytometry/Cell sorting to assess whether, or to what degree, random monoallelic expression of autosomal genes is mitotically inherited or stochastic in somatic cells, particularly in vivo.
Tue Nov 01 00:00:00 EDT 2016
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.
Scientific reports
Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education.
Journal of immunology (Baltimore, Md. : 1950)
Marquardt N,Ivarsson MA,Blom K,Gonzalez VD,Braun M,Falconer K,Gustafsson R,Fogdell-Hahn A,Sandberg JK,Michaëlsson J
15-0049 was used in Flow cytometry/Cell sorting to study the temporal dynamics and regulation of natural killer cell responses in an acute viral infection.
Thu Oct 01 00:00:00 EDT 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
15-0049 was used in Flow cytometry/Cell sorting to establish a correlation between low levels of glutathione and an increased susceptibility to M. tuberculosis infection.
Sun Nov 01 00:00:00 EDT 2015
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
15-0049 was used in Flow cytometry/Cell sorting to study the mechanisms of reduced levels of glutathione in sufferers of type II diabetes and the effect of this on susceptibility to tuberculosis infection.
Wed Dec 30 00:00:00 EST 2015
The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination.
PloS one
Vettermann C,Timblin GA,Lim V,Lai EC,Schlissel MS
15-0049 was used in Flow cytometry/Cell sorting to identify the proximal GT promoter as the first cis-element known to regulate the internal order of Jκ rearrangements.
Tue Jan 26 00:00:00 EST 2016
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR.
British journal of pharmacology
Vinet J,van Zwam M,Dijkstra IM,Brouwer N,van Weering HR,Watts A,Meijer M,Fokkens MR,Kannan V,Verzijl D,Vischer HF,Smit MJ,Leurs R,Biber K,Boddeke HW
15-0049 was used in Flow cytometry/Cell sorting to study the role of hCCX-CKR in hCXCR3-induced chemotaxis.
Fri Mar 01 00:00:00 EST 2013
Immunosuppressive effect of regulatory T lymphocytes in lung cancer, with special reference to their effects on the induction of autologous tumor-specific cytotoxic T lymphocytes.
Oncology letters
Shigematsu Y,Hanagiri T,Shiota H,Kuroda K,Baba T,Ichiki Y,Yasuda M,Uramoto H,Takenoyama M,Yasumoto K,Tanaka F
15-0049 was used in Flow cytometry/Cell sorting to analyse the distribution of Tregs among tumour-infiltrating lymphocytes, regional lymph node lymphocytes and peripheral blood lymphocytes in patients with lung cancer.
Mon Oct 01 00:00:00 EDT 2012
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
Evidence for local dendritic cell activation in pulmonary sarcoidosis.
Respiratory research
Ten Berge B,Kleinjan A,Muskens F,Hammad H,Hoogsteden HC,Hendriks RW,Lambrecht BN,Van den Blink B
15-0049 was used in Flow cytometry/Cell sorting to determine whether, at sites of sarcoidosis, dendritic cells are involved in granuloma formation and maintenance.
Wed Apr 18 00:00:00 EDT 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery.
Molecular pharmaceutics
Park J,Gao W,Whiston R,Strom TB,Metcalfe S,Fahmy TM
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2011
Genome-wide identification of human FOXP3 target genes in natural regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Sadlon TJ,Wilkinson BG,Pederson S,Brown CY,Bresatz S,Gargett T,Melville EL,Peng K,D'Andrea RJ,Glonek GG,Goodall GJ,Zola H,Shannon MF,Barry SC
15-0049 was used in Flow cytometry/Cell sorting to demonstrate that in conjunction with CD25, peptidase inhibitor 16 may be a surrogate surface marker for regulatory T-cells.
Thu Jul 15 00:00:00 EDT 2010
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD4 monoclonal antibody (Product # 15-0049-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
15-0049 was used in Flow cytometry/Cell sorting to study the increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity, in B cells and monocytes from patients with active multiple sclerosis.
Mon Nov 16 00:00:00 EST 2009
Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
The Journal of biological chemistry
Chen IJ,Chen HL,Demetriou M
15-0049 was used in Flow cytometry/Cell sorting to investigate the role of the galectin lattice and actin cytoskeleton in controlling microdomain structure and coordinating signal transduction across the plasma membrane.
Fri Nov 30 00:00:00 EST 2007
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
Respiratory research
Mansson A,Adner M,Cardell LO
15-0049 was used in Flow cytometry/Cell sorting to investigate the role of toll-like receptors in human tonsil CD4+ and CD8+ T cells, and their altered expression in patients with recurrent tonsillitis.
Mon Feb 27 00:00:00 EST 2006