Product References
Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques.
NPJ vaccines
Vierboom MPM,Chenine AL,Darrah PA,Vervenne RAW,Boot C,Hofman SO,Sombroek CC,Dijkman K,Khayum MA,Stammes MA,Haanstra KG,Hoffmann C,Schmitt D,Silvestre N,White AG,Borish HJ,Seder RA,Ouaked N,Leung-Theung-Long S,Inchauspé G,Anantha R,Limbach M,Evans TG,Casimiro D,Lempicki M,Laddy DJ,Bonavia A,Verreck FAW
MHCD0418 was used in Flow cytometry/Cell sorting to show that TB manifestation after full parenteral vaccination was significantly less compared to exclusive mucosal vaccination.
Mon Aug 16 00:00:00 EDT 2021
Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways.
Cell reports. Medicine
Herati RS,Silva LV,Vella LA,Muselman A,Alanio C,Bengsch B,Kurupati RK,Kannan S,Manne S,Kossenkov AV,Canaday DH,Doyle SA,Ertl HCJ,Schmader KE,Wherry EJ
MHCD0418 was used in Flow Cytometry to highlight the ability to use vaccine-induced cTfh as cellular "biosensors" of underlying inflammatory and/or overall immune health.
Tue May 18 00:00:00 EDT 2021
Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center.
NPJ vaccines
Eslamizar L,Petrovas C,Leggat DJ,Furr K,Lifton ML,Levine G,Ma S,Fletez-Brant C,Hoyland W,Prabhakaran M,Narpala S,Boswell K,Yamamoto T,Liao HX,Pickup D,Ramsburg E,Sutherland L,McDermott A,Roederer M,Montefiori D,Koup RA,Haynes BF,Letvin NL,Santra S
Published figure using CD4 monoclonal antibody (Product # MHCD0418) in Flow Cytometry
Mon Jan 25 00:00:00 EST 2021
CD57+ Memory T Cells Proliferate In Vivo.
Cell reports
Ahmed R,Miners KL,Lahoz-Beneytez J,Jones RE,Roger L,Baboonian C,Zhang Y,Wang ECY,Hellerstein MK,McCune JM,Baird DM,Price DA,Macallan DC,Asquith B,Ladell K
Published figure using CD4 monoclonal antibody (Product # MHCD0418) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Cell
Sekine T,Perez-Potti A,Rivera-Ballesteros O,Strålin K,Gorin JB,Olsson A,Llewellyn-Lacey S,Kamal H,Bogdanovic G,Muschiol S,Wullimann DJ,Kammann T,Emgård J,Parrot T,Folkesson E,Rooyackers O,Eriksson LI,Henter JI,Sönnerborg A,Allander T,Albert J,Nielsen M,Klingström J,Gredmark-Russ S,Björkström NK,Sandberg JK,Price DA,Ljunggren HG,Aleman S,Buggert M
Published figure using CD4 monoclonal antibody (Product # MHCD0418) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Cell
Sekine T,Perez-Potti A,Rivera-Ballesteros O,Strålin K,Gorin JB,Olsson A,Llewellyn-Lacey S,Kamal H,Bogdanovic G,Muschiol S,Wullimann DJ,Kammann T,Emgård J,Parrot T,Folkesson E,Rooyackers O,Eriksson LI,Henter JI,Sönnerborg A,Allander T,Albert J,Nielsen M,Klingström J,Gredmark-Russ S,Björkström NK,Sandberg JK,Price DA,Ljunggren HG,Aleman S,Buggert M
Published figure using CD4 monoclonal antibody (Product # MHCD0418) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Interferon-α alters host glycosylation machinery during treated HIV infection.
EBioMedicine
Giron LB,Colomb F,Papasavvas E,Azzoni L,Yin X,Fair M,Anzurez A,Damra M,Mounzer K,Kostman JR,Tebas P,O'Doherty U,Tateno H,Liu Q,Betts MR,Montaner LJ,Abdel-Mohsen M
MHCD0418 was used in Flow cytometry/Cell sorting to identify significant interactions that support a model in which a) IFNα increases the proportion of pro-inflammatory, bisecting GlcNAc glycans (known to enhance FcγR binding) within the IgG glycome, which in turn b) increases inflammation, which c) leads to poor CD8+ T cell phenotypes and poor IFNα-mediated reduction of HIV DNA.
Tue Sep 01 00:00:00 EDT 2020
Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity.
Cell reports
Ols S,Yang L,Thompson EA,Pushparaj P,Tran K,Liang F,Lin A,Eriksson B,Karlsson Hedestam GB,Wyatt RT,Loré K
MHCD0418 was used in Flow Cytometry to identify the anatomical compartments and early immune processes engaged in the response to immunization via intramuscular (i.m.) administration and subcutaneous (s.c.) delivery.
Tue Mar 24 00:00:00 EDT 2020
Longitudinal variation in human immunodeficiency virus long terminal repeat methylation in individuals on suppressive antiretroviral therapy.
Clinical epigenetics
Cortés-Rubio CN,Salgado-Montes de Oca G,Prado-Galbarro FJ,Matías-Florentino M,Murakami-Ogasawara A,Kuri-Cervantes L,Carranco-Arenas AP,Ormsby CE,Cortés-Rubio IK,Reyes-Terán G,Ávila-Ríos S
MHCD0418 was used in Flow cytometry/Cell sorting to report methylation patterns on HIV 5'-LTR in total CD4+ T cells is dynamic along time and that it can follow different temporal patterns that are associated with a combination of baseline and follow-up clinical characteristics.
Fri Sep 13 00:00:00 EDT 2019
Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes.
The Journal of clinical investigation
Yeo L,Woodwyk A,Sood S,Lorenc A,Eichmann M,Pujol-Autonell I,Melchiotti R,Skowera A,Fidanis E,Dolton GM,Tungatt K,Sewell AK,Heck S,Saxena A,Beam CA,Peakman M
MHCD0418 was used in Flow cytometry/Cell sorting to determine disease relevance of B cell reactive CD8+ T cells and their relationship to B cell function in type 1 diabetes.
Wed Aug 01 00:00:00 EDT 2018
Gut Homing CD4+ and CD8+ T-Cell Frequencies in HIV Infected Individuals on Antiretroviral Treatment.
PloS one
Briceño O,Pinto-Cardoso S,Rodríguez-Bernabe N,Murakami-Ogasawara A,Reyes-Terán G
Published figure using CD4 monoclonal antibody (Product # MHCD0418) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2017
Fecal Bacterial Communities in treated HIV infected individuals on two antiretroviral regimens.
Scientific reports
Pinto-Cardoso S,Lozupone C,Briceño O,Alva-Hernández S,Téllez N,Adriana A,Murakami-Ogasawara A,Reyes-Terán G
MHCD0418 was used in flow cytometry to investigate the fecal microbiomes of HIV-uninfected to HIV-infected individuals on long-term antiretroviral therapy
Mon Mar 06 00:00:00 EST 2017
Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
Scientific reports
Tauriainen J,Scharf L,Frederiksen J,Naji A,Ljunggren HG,Sönnerborg A,Lund O,Reyes-Terán G,Hecht FM,Deeks SG,Betts MR,Buggert M,Karlsson AC
MHCD0418 was used in flow cytometry to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment
Fri Jan 13 00:00:00 EST 2017
Selective reduction of IFN-γ single positive mycobacteria-specific CD4+ T cells in HIV-1 infected individuals with latent tuberculosis infection.
Tuberculosis (Edinburgh, Scotland)
Riou C,Bunjun R,Müller TL,Kiravu A,Ginbot Z,Oni T,Goliath R,Wilkinson RJ,Burgers WA
MHCD0418 was used in flow cytometry to explore how HIV-1 alters immunity during latent tuberculosis
Thu Dec 01 00:00:00 EST 2016
Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.
PLoS pathogens
Roberts ER,Carnathan DG,Li H,Shaw GM,Silvestri G,Betts MR
MHCD0418 was used in flow cytometry to examine the kinetics of SIV-specific CD8+ T cell cytolytic factor expression in peripheral blood, lymph node, spleen, and gut mucosa from early acute infection through chronic infection
Thu Dec 01 00:00:00 EST 2016
Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
PLoS pathogens
Demers KR,Makedonas G,Buggert M,Eller MA,Ratcliffe SJ,Goonetilleke N,Li CK,Eller LA,Rono K,Maganga L,Nitayaphan S,Kibuuka H,Routy JP,Slifka MK,Haynes BF,McMichael AJ,Bernard NF,Robb ML,Betts MR
MHCD0418 was used in flow cytometry to study the cytolytic effector capacity of HIV-specific CD8+ T cells
Mon Aug 01 00:00:00 EDT 2016
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Nature medicine
Vaccari M,Gordon SN,Fourati S,Schifanella L,Liyanage NP,Cameron M,Keele BF,Shen X,Tomaras GD,Billings E,Rao M,Chung AW,Dowell KG,Bailey-Kellogg C,Brown EP,Ackerman ME,Vargas-Inchaustegui DA,Whitney S,Doster MN,Binello N,Pegu P,Montefiori DC,Foulds K,Quinn DS,Donaldson M,Liang F,Loré K,Roederer M,Koup RA,McDermott A,Ma ZM,Miller CJ,Phan TB,Forthal DN,Blackburn M,Caccuri F,Bissa M,Ferrari G,Kalyanaraman V,Ferrari MG,Thompson D,Robert-Guroff M,Ratto-Kim S,Kim JH,Michael NL,Phogat S,Barnett SW,Tartaglia J,Venzon D,Stablein DM,Alter G,Sekaly RP,Franchini G
MHCD0418 was used in flow cytometry to optimize vaccination with Aventis Pasteur's canarypox vector-HIV
Fri Jul 01 00:00:00 EDT 2016
Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs.
Journal of virology
Bolton DL,Pegu A,Wang K,McGinnis K,Nason M,Foulds K,Letukas V,Schmidt SD,Chen X,Todd JP,Lifson JD,Rao S,Michael NL,Robb ML,Mascola JR,Koup RA
MHCD0418 was used in flow cytometry to assess the ability of HIV-1 envelope glycoprotein-specific broadly neutralizing monoclonal antibodies to suppress acute simian-human immunodeficiency virus replication in rhesus macaques
Mon Feb 01 00:00:00 EST 2016
A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion.
PloS one
Riou C,Gray CM,Lugongolo M,Gwala T,Kiravu A,Deniso P,Stewart-Isherwood L,Omar SV,Grobusch MP,Coetzee G,Conradie F,Ismail N,Kaplan G,Fallows D
MHCD0418 was used in Flow cytometry/Cell sorting to investigate 18 HIV-negative patients with MDR-TB for M. tuberculosis (Mtb)- and PPD-specific CD4 T cell responses and followed them over 6 months of drug therapy.
Tue Apr 07 00:00:00 EDT 2015
Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humans.
Human gene therapy
Parzych EM,Li H,Yin X,Liu Q,Wu TL,Podsakoff GM,High KA,Levine MH,Ertl HC
MHCD0418 was used in immunocytochemistry to assess the effect of immunosuppression used for organ transplantation on immune responses to adeno-associated virus capsid antigens.
Mon Apr 01 00:00:00 EDT 2013
Capsid-specific T-cell responses to natural infections with adeno-associated viruses in humans differ from those of nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy
Li H,Lasaro MO,Jia B,Lin SW,Haut LH,High KA,Ertl HC
MHCD0418 was used in flow cytometry to test if rejection of AAV-transduced hepatocytes is due to AAV capsid-specific CD8 positive T cells that become reactivated upon gene transfer.
Tue Nov 01 00:00:00 EDT 2011
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
Journal of immunology (Baltimore, Md. : 1950)
Clement M,Ladell K,Ekeruche-Makinde J,Miles JJ,Edwards ES,Dolton G,Williams T,Schauenburg AJ,Cole DK,Lauder SN,Gallimore AM,Godkin AJ,Burrows SR,Price DA,Sewell AK,Wooldridge L
MHCD0418 was used in flow cytometry to test if anti-CD8 Abs induce effector function.
Fri Jul 15 00:00:00 EDT 2011
