Product References
Ultrasound combined with nanobubbles promotes systemic anticancer immunity and augments anti-PD1 efficacy.
Journal for immunotherapy of cancer
Hu J,He J,Wang Y,Zhao Y,Fang K,Dong Y,Chen Y,Zhang Y,Zhang C,Wang H,Tan J,Wang J,Zi R,Liu C,Liang H,Guo Y,Ou J
25-5971-82 was used in Flow Cytometry to provide a promising strategy for sensitizing poorly immunogenic solid tumors to immunotherapy in the clinic.
Tue Mar 01 00:00:00 EST 2022
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 25-5971-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Nature communications
Zhao Z,Wang H,Shi M,Zhu T,Pediongco T,Lim XY,Meehan BS,Nelson AG,Fairlie DP,Mak JYW,Eckle SBG,de Lima Moreira M,Tumpach C,Bramhall M,Williams CG,Lee HJ,Haque A,Evrard M,Rossjohn J,McCluskey J,Corbett AJ,Chen Z
25-5971-82 was used in Flow Cytometry to highlight the potential utility of targeting MAIT cells to combat a range of bacterial pathogens.
Fri Jul 16 00:00:00 EDT 2021
Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2.
iScience
Park JG,Oladunni FS,Rohaim MA,Whittingham-Dowd J,Tollitt J,Hodges MDJ,Fathallah N,Assas MB,Alhazmi W,Almilaibary A,Iqbal M,Chang P,Escalona R,Shivanna V,Torrelles JB,Worthington JJ,Jackson-Jones LH,Martinez-Sobrido L,Munir M
25-5971-82 was used in Flow Cytometry to evaluate a Newcastle disease virus (NDV)-based vectored-vaccine in mice and hamsters for its immunogenicity, safety and protective efficacy against SARS-CoV-2.
Fri Sep 24 00:00:00 EDT 2021
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
25-5971 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 EDT 2020
IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell-Dependent Route.
Journal of immunology (Baltimore, Md. : 1950)
Iglesias-Guimarais V,Ahrends T,de Vries E,Knobeloch KP,Volkov A,Borst J
25-5971 was used in Flow cytometry/Cell sorting to conclude that free ISG15 is part of a newly recognized innate route to promote the CTL response.
Wed Apr 15 00:00:00 EDT 2020
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy.
Cell reports
Hirukawa A,Singh S,Wang J,Rennhack JP,Swiatnicki M,Sanguin-Gendreau V,Zuo D,Daldoul K,Lavoie C,Park M,Andrechek ER,Westbrook TF,Harris LN,Varadan V,Smith HW,Muller WJ
25-5971-82 was used in Flow cytometry/Cell sorting to provide evidence that EZH2 inhibitors promote interferon-driven immune responses that enhance the efficacy of anti-ErbB2 mAbs, suggesting the potential clinical benefit of epigenomic reprogramming by H3K27me3 depletion in Trastuzumab-resistant disease.
Tue Oct 08 00:00:00 EDT 2019
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.
Cell
Aguilar OA,Berry R,Rahim MMA,Reichel JJ,Popović B,Tanaka M,Fu Z,Balaji GR,Lau TNH,Tu MM,Kirkham CL,Mahmoud AB,Mesci A,Krmpotić A,Allan DSJ,Makrigiannis AP,Jonjić S,Rossjohn J,Carlyle JR
25-5971 was used in Flow cytometry/Cell sorting to identify a viral ligand for the inhibitory and activating NKR-P1 receptors.
Thu Mar 23 00:00:00 EDT 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 25-5971-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia.
PLoS pathogens
Cnops J,De Trez C,Stijlemans B,Keirsse J,Kauffmann F,Barkhuizen M,Keeton R,Boon L,Brombacher F,Magez S
25-5971 was used in Flow cytometry/Cell sorting to show that NK, NKT and CD8+ T cell-derived IFNγ is a critical mediator in trypanosomosis-associated pathology.
Mon Jun 01 00:00:00 EDT 2015
VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.
Journal of immunology (Baltimore, Md. : 1950)
Palmer VL,Aziz-Seible R,Kassmeier MD,Rothermund M,Perry GA,Swanson PC
25-5971 was used in Flow cytometry/Cell sorting to determine the contribution of the protein, VprBP, to B cell development and selection.
Sat Aug 15 00:00:00 EDT 2015
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.
PLoS genetics
Gralinski LE,Ferris MT,Aylor DL,Whitmore AC,Green R,Frieman MB,Deming D,Menachery VD,Miller DR,Buus RJ,Bell TA,Churchill GA,Threadgill DW,Katze MG,McMillan L,Valdar W,Heise MT,Pardo-Manuel de Villena F,Baric RS
25-5971 was used in Flow cytometry/Cell sorting to validate the Collaborative Cross platform as a resource for uncovering the genetic contributions of complex traits in microbial diseases, inflammation and viral replication.
Thu Oct 01 00:00:00 EDT 2015
Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity.
Cancer research
Cecil DL,Holt GE,Park KH,Gad E,Rastetter L,Childs J,Higgins D,Disis ML
25-5971 was used in Flow cytometry/Cell sorting to investigate the deletion of immunosuppressive epitopes from an IGFBP-2 cancer vaccine as a novel strategy to increase antitumor activity.
Thu May 15 00:00:00 EDT 2014
Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo.
PloS one
Wu X,Satpathy AT,Kc W,Liu P,Murphy TL,Murphy KM
25-5971 was used in Flow cytometry/Cell sorting to investigate the role of Bcl11a in the development of dendritic cells, showing that it controls Flt3 expression in early hematopoietic progenitors and is required for pDC development.
Fri Jan 10 00:00:00 EST 2014
Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.
The Journal of biological chemistry
Patnode ML,Cheng CW,Chou CC,Singer MS,Elin MS,Uchimura K,Crocker PR,Khoo KH,Rosen SD
25-5971 was used in Flow cytometry/Cell sorting to investigate whether keratan sulfate galactose 6-O-sulfotransferase and chondroitin 6-O-sulfotransferase 1 are required for the generation of endogenous Siglec-F ligands.
Fri Sep 13 00:00:00 EDT 2013
Phenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice.
PloS one
Camp JV,Chu YK,Chung DH,McAllister RC,Adcock RS,Gerlach RL,Wiemken TL,Peyrani P,Ramirez JA,Summersgill JT,Jonsson CB
25-5971 was used in Flow cytometry/Cell sorting to capture the possible genotypic and phenotypic differences of the 2009 influenza A virus H1N1 pandemic strains circulating in adult hospitalized patients.
Tue Aug 13 00:00:00 EDT 2013
STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice.
Journal of immunology (Baltimore, Md. : 1950)
O'Donnell LA,Conway S,Rose RW,Nicolas E,Slifker M,Balachandran S,Rall GF
25-5971 was used in Flow cytometry/Cell sorting to determine whether STAT1 is required for IFN-γ-mediated protection from infection in neurons, showing that absence of STAT1 in mice did not restrict the ability of IFN-γ to control viral infection, through a pathway independent of the usual pathway.
Wed Feb 15 00:00:00 EST 2012
Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion.
Infection and immunity
Smith KA,Harcus Y,Garbi N,Hämmerling GJ,MacDonald AS,Maizels RM
25-5971 was used in Flow cytometry/Cell sorting to investigate the type 2 response to intestinal nematode parasites, showing that it is induced redundantly and acts autonomously following CD11c(+) cell depletion.
Mon Oct 01 00:00:00 EDT 2012
IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice.
PloS one
Loebbermann J,Schnoeller C,Thornton H,Durant L,Sweeney NP,Schuijs M,O'Garra A,Johansson C,Openshaw PJ
25-5971 was used in Flow cytometry/Cell sorting to study experimental respiratory syncytial virus infection in IL-10 deficient mice and mice treated with anti-IL-10 receptor antibody.
Mon Jul 23 00:00:00 EDT 2012
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity.
Nature immunology
Liang HE,Reinhardt RL,Bando JK,Sullivan BM,Ho IC,Locksley RM
25-5971 was used in Flow cytometry/Cell sorting to assess the temporal and spatial production of IL-4 and IL-13 in vivo.
Sun Dec 04 00:00:00 EST 2011
CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge.
PLoS pathogens
Matullo CM,O'Regan KJ,Curtis M,Rall GF
25-5971 was used in Flow cytometry/Cell sorting to indicate that CD8+ T-cell recruitment to the brain can trigger CNS disease in the apparent absence of cognate antigen.
Thu Dec 01 00:00:00 EST 2011
Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Smith KA,Hochweller K,Hämmerling GJ,Boon L,MacDonald AS,Maizels RM
25-5971 was used in Magnetic cell separation to identify that the preferential expansion of a novel population of CD11c(lo) non-plasmacytoid DCs is associated with the pro-regulatory environment of chronic intestinal helminth infection.
Wed Jun 15 00:00:00 EDT 2011
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17.
Journal of leukocyte biology
Nakae S,Iwakura Y,Suto H,Galli SJ
25-5971 was used in Functional assays to compare the cell surface marker expression profiles of Th1 and Th17 cells.
Tue May 01 00:00:00 EDT 2007
A new approach for analyzing cellular infiltration during allergic airway inflammation.
Journal of immunological methods
Hoffmann PR,Gurary A,Hoffmann FW,Jourdan-Le Saux C,Teeters K,Hashimoto AC,Tam EK,Berry MJ
25-5971 was used in Flow cytometry/Cell sorting to investigate a new approach for analyzing cellular infiltration during allergic airway inflammation.
Sat Dec 01 00:00:00 EST 2007