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IL-17D Monoclonal Antibody (1D7H4), CoraLite® Plus 488
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FIGURE: 1 / 1
IL-17D Antibody (CL488-66143) in Flow
1X10^6 Jurkat cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human IL-17D (CL488-66143, Clone:1D7H4) (red), or 0.4 µg Mouse IgG2b Isotype Control (CL488-66360-3, Clone: K11B8C4B5) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-66143
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1D7H4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MLVAGFLLAL PPSWAAGAPR AGRRPARPRG CADRPEELLE QLYGRLAAGV LSAFHHTLQL GPREQARNAS CPAGGRPADR RFRPPTNLRS VSPWAYRISY DPARYPRYLP EAYCLCRGCL TGLFGEEDVR FRSAPVYMPT VVLRRTPACA GGRSVYTEAY VTIPVGCTCV PEPEKDADSI NSSIDKQGAK LLLGPNDAPA GP
Target Information
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine; FLJ30846; IL-17D; IL-22; IL-27; IL-3R; Interleukin; Interleukin-17D; Interleukin-27
Gene Aliases: IL-17D; IL17D; UNQ3096/PRO21175
UniProt ID: (Human) Q8TAD2
Entrez Gene ID: (Human) 53342
inflammatory response
signal transduction
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of cytokine production involved in inflammatory response
negative regulation of hemopoiesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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