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Proteintech
IL-17D Monoclonal Antibody (1D7H4)
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Product Details
66143-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1D7H4
Immunogen
IL-17D Fusion Protein Ag6762 (1-202 aa encoded by BC036243)
Conjugate
Form
Liquid
Concentration
1.33 mg/mL
Amount
199.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLVAGFLLA LPPSWAAGAP RAGRRPARPR GCADRPEELL EQLYGRLAAG VLSAFHHTLQ LGPREQARNA SCPAGGRPAD RRFRPPTNLR SVSPWAYRIS YDPARYPRYL PEAYCLCRGC LTGLFGEEDV RFRSAPVYMP TVVLRRTPAC AGGRSVYTEA YVTIPVGCTC VPEPEKDADS INSSIDKQGA KLLLGPNDAP AGP (1-202 aa encoded by BC036243)
Target Information
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytokine; FLJ30846; IL-17D; IL-22; IL-27; IL-3R; Interleukin; Interleukin-17D; Interleukin-27
Gene Aliases: IL-17D; IL17D; UNQ3096/PRO21175
UniProt ID: (Human) Q8TAD2
Entrez Gene ID: (Human) 53342
inflammatory response
signal transduction
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of cytokine production involved in inflammatory response
negative regulation of hemopoiesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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