Search
Proteintech
CAPN2 Monoclonal Antibody (1E1F10), CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
CL488-66977
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E1F10
Immunogen
CAPN2 fusion protein Ag28427
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAGIAAKLAK DREAAEGLGS HERAIKYLNQ DYEALRNECL EAGTLFQDPS FPAIPSALGF KELGPYSSKT RGIEWKRPTE ICADPQFIIG GATRTDICQG ALGDCWLLAA IASLTLNEEI LARVVPLNQS FQENYAGIFH FQFWQYGEWV EVVVDDRLPT KDGELLFVHS AEGSEFWSAL LEKAYAKING CYEALSGGAT TEGFEDFTGG IAEWYELKKP PPNLFKIIQK ALQKGSLLGC SIDITSAADS EAITFQKLVK GHAYSVTGAE EVESNGSLQK LIRIRNPWGE VEWTGRWNDN CPSWNTIDPE ERERLTRRHE DGEFWMSFSD
Target Information
Mu-Calpain, also known as Calpain-I, and m-calpain, also known as Calpain-II, are intracellular, calcium-dependent cysteine proteases. Mu-calpain has a micromolar sensitivity (thus the mu-) as compared to the millimolar calcium sensitivity of m-calpain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 80 kDa M-calpain subunit; Ca2-activated neutral protease subunit; Calcium-activated neutral proteinase 2; CALP80; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; Calpain large polypeptide L2; Calpain M-type; calpain, large polypeptide L2; Calpain-2 catalytic subunit; Calpain-2 large subunit; CANP 2; cysteine proteinase; M-calpain; m-calpain 80 kDa large subunit; m-calpain large subunit; Millimolar-calpain; unnamed protein product
Gene Aliases: AI326419; CANP2; CANPL2; CANPml; Capa-2; Capa2; CAPN2; m-calpain; m-calpin; mCANP
UniProt ID: (Human) P17655, (Mouse) O08529, (Rat) Q07009
Entrez Gene ID: (Human) 824, (Mouse) 12334, (Rat) 29154
calcium-dependent cysteine-type endopeptidase activity
calcium ion binding
protein binding
cytoskeletal protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
enzyme binding
macromolecular complex binding
metal ion binding
protein heterodimerization activity
cysteine protease
response to hypoxia
blastocyst development
proteolysis
myoblast fusion
female pregnancy
response to mechanical stimulus
positive regulation of cardiac muscle cell apoptotic process
protein autoprocessing
protein catabolic process
regulation of interleukin-6 production
cellular response to interferon-beta
response to hydrogen peroxide
behavioral response to pain
synaptic vesicle endocytosis
regulation of cytoskeleton organization
proteolysis involved in cellular protein catabolic process
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
vascular endothelial cell response to laminar fluid shear stress
vascular endothelial cell response to oscillatory fluid shear stress
protein catabolic process at postsynapse
positive regulation of myoblast fusion
positive regulation of phosphatidylcholine biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support