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CNBP Monoclonal Antibody (1H1D12), CoraLite® Plus 488
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FIGURE: 1 / 1
CNBP Antibody (CL488-67109) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human CNBP (CL488-67109, Clone:1H1D12) (red), or 0.4 µg Mouse IgG2a Isotype Control (CL488-66360-2, Clone: K11A1B2A2) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-67109
Product Specifications
Species Reactivity
Rat,
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1H1D12
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSSNECFKCG RSGHWARECP TGGGRGRGMR SRGRGFQFVS SSLPDICYRC GESGHLAKDC DLQEDACYNC GRGGHIAKDC KEPKREREQC CYNCGKPGHL ARDCDHADEQ KCYSCGEFGH IQKDCTKVKC YRCGETGHVA INCSKTSEVN CYRCGESGHL ARECTIEATA
Target Information
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCHC-type zinc finger nucleic acid binding protein; cellular nucleic acid binding protein 1; Cellular nucleic acid-binding protein; CNBP; erythroid differentiation-related; HGNC:13164; sterol regulatory element-binding protein; unnamed protein product; zinc finger protein; zinc finger protein 273; Zinc finger protein 9; zinc finger protein 9 (a cellular retroviral nucleic acid binding protein); zinc finger protein; hCNBP
Gene Aliases: AA408710; CNBP; CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9
UniProt ID: (Human) P62633, (Mouse) P53996, (Rat) P62634
Entrez Gene ID: (Human) 7555, (Mouse) 12785, (Rat) 64530
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of cell proliferation
cholesterol homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
G-quadruplex DNA formation
positive regulation of cytoplasmic translation
transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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