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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MUNC18 Antibodies

          Proteintech

          STXBP1 Monoclonal Antibody (1B5B3), CoraLite® Plus 488

          View all (17) MUNC18 antibodies

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          Cite STXBP1 Monoclonal Antibody (1B5B3), CoraLite® Plus 488

          Additional Information:
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          • Antibody Testing Data (2)
          STXBP1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          STXBP1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          STXBP1 Antibody (CL488-67137) in WB

          Various lysates were subjected to SDS PAGE followed by western blot with CL488-67137 (STXBP1 antibody) at dilution of 1:2,000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          STXBP1 Antibody in Western Blot (WB)
          STXBP1 Antibody in Flow Cytometry (Flow)

          Product Details

          CL488-67137

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          -

          Flow Cytometry (Flow)

          0.80 µg/10^6 cells in a 100 µL suspension
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1B5B3

          Immunogen

          STXBP1 fusion protein Ag28605

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • Biotin 
          • CoraLite 594
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: HELTFQAMS YDLLPIENDV YKYETSGIGE ARVKEVLLDE DDDLWIALRH KHIAEVSQEV TRSLKDFSSS KRMNTGEKTT MRDLSQMLKK MPQYQKELSK YSTHLHLAED CMKHYQGTVD KLCRVEQDLA MGTDAEGEKI KDPMRAIVPI LLDANVSTYD KIRIILLYIF LKNGITEENL NKLIQHAQIP PEDSEIITNM AHLGVPIVTD STLRRRSKPE RKERISEQTY QLSRWTPIIK DIMEDTIEDK LDTKHYPYIS TRSSASFSTT AVSARYGHWH KNKAPGEYRS GPRLIIFILG GVSLNEMRCA YEVTQANGKW EVLIGSTHIL TPQKLLDTLK KLNKTDEEIS S

          Target Information

          This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rbSec1; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1

          View more View less

          Gene Aliases: AI317162; AI326233; ANC18HA; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-sec1; NSEC1; NSEC1A; P67; Rb-sec1; RBSEC1; rbSec1A; rbSec1B; Sec1; STXBP1; Sxtbp1; UNC18; Unc18-1; UNC18A; Unc18h

          View more View less

          UniProt ID: (Human) P61764, (Mouse) O08599, (Rat) P61765

          View more View less

          Entrez Gene ID: (Human) 6812, (Mouse) 20910, (Rat) 25558

          View more View less

          Function(s)
          SNARE binding protein binding syntaxin-1 binding protein kinase binding protein domain specific binding syntaxin binding identical protein binding poly(A) RNA binding protein N-terminus binding membrane trafficking regulatory protein
          Process(es)
          platelet degranulation vesicle docking involved in exocytosis neurotransmitter secretion neuromuscular synaptic transmission axon target recognition regulation of synaptic vesicle priming glutamate secretion protein transport synaptic vesicle maturation regulation of synaptic vesicle fusion to presynaptic membrane negative regulation of synaptic transmission, GABAergic regulation of SNARE complex assembly negative regulation of neuron apoptotic process positive regulation of calcium ion-dependent exocytosis protein stabilization long term synaptic depression platelet aggregation protein localization to plasma membrane transport exocytosis vesicle-mediated transport synaptic vesicle fusion to presynaptic active zone membrane positive regulation of exocytosis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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