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Proteintech
ARP3/ARP3B Monoclonal Antibody (1D12C7), CoraLite® Plus 488
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Product Details
CL488-68439
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D12C7
Immunogen
ARP3/ARP3B fusion protein Ag5017
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: RQVGERTLTG TVIDSGDGVT HVIPVAEGYV IGSCIKHIPI AGRDITYFIQ QLLRDREVGI PPEQSLETAK AVKERYSYVC PDLVKEFNKY DTDGSKWIKQ YTGINAISKK EFSIDVGYER FLGPEIFFHP EFANPDFTQP ISEVVDEVIQ NCPIDVRRPL YKNIVLSGGS TMFRDFGRRL QRDLKRTVDA RLKLSEELSG GRLKPKPIDV QVITHHMQRY AVWFGGSMLA STPEFYQVCH TKKDYEEIGP SICRHNPVFG VMS
Target Information
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 3; Actin-related protein 3; actin-related protein 3 homolog (yest); ARP3 actin related protein 3 homolog; ARP3 actin-related protein 3 homolog; one of seven subunits of the Arp2/3 protein complex; unnamed protein product
Gene Aliases: 1200003A09Rik; ACTR3; ARP3
UniProt ID: (Human) P61158, (Rat) Q4V7C7, (Mouse) Q99JY9
Entrez Gene ID: (Rabbit) 100008790, (Human) 10096, (Pig) 396738, (Rat) 81732, (Mouse) 74117
establishment or maintenance of cell polarity
asymmetric cell division
positive regulation of lamellipodium assembly
meiotic chromosome movement towards spindle pole
cell projection organization
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
positive regulation of transcription from RNA polymerase II promoter
meiotic cell cycle
spindle localization
cilium morphogenesis
actin polymerization-dependent cell motility
cellular response to interferon-gamma
response to carbohydrate
positive regulation of actin filament polymerization
regulation of myosin II filament organization
positive regulation of neuron differentiation
response to antibiotic
positive regulation of dendrite morphogenesis
positive regulation of filopodium assembly
actin filament organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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