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Proteintech
FANCM Recombinant Rabbit Monoclonal Antibody (230233G5), CoraLite® Plus 488
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Product Details
CL488-82897-2
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
230233G5
Immunogen
FANCM fusion protein Ag34447
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VARKFLDDEA ELSEEDAEYV SSDENDESEN EQDSSLLDFL NDETQLSQAI NDSEMRAIYM KSLRSPMMNN KYKMIHKTHK NINIFSQIPE QDETYLEDSF CVDEEESCKG QSSEEEVCVD FNLITDDCFA NSKKYKTRRA VMLKEMMEQN CAHSKKKLSR IILPDDSSEE ENNVNDKRES NIAVNPSTVK KNKQQDHCL
Target Information
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase FANCM; FAAP250; FANCM; Fanconi anemia complementation group M; Fanconi anemia group M protein; Fanconi anemia-associated polypeptide of 250 kDa; Protein FACM; Protein Hef ortholog; unnamed protein product
Gene Aliases: FAAP250; FANCM; KIAA1596; POF15; SPGF28
UniProt ID: (Human) Q8IYD8
Entrez Gene ID: (Human) 57697
resolution of meiotic recombination intermediates
DNA repair
cellular response to DNA damage stimulus
replication fork processing
reciprocal DNA recombination
interstrand cross-link repair
double-strand break repair via synthesis-dependent strand annealing
positive regulation of protein monoubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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