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Proteintech
CELSR2 Recombinant Rabbit Monoclonal Antibody (230319H5), CoraLite® Plus 488
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Product Details
CL488-83115
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
230319H5
Immunogen
Peptide
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adhesion G protein-coupled receptor C2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; Epidermal growth factor-like protein 2; Flamingo homolog 3; FLJ34118; FLJ42737; FLJ45143; FLJ45845; multiple EGF like domains 3; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3; unnamed protein product
Gene Aliases: ADGRC2; CDHF10; CELSR2; EGFL2; Flamingo1; KIAA0279; MEGF3
UniProt ID: (Human) Q9HCU4
Entrez Gene ID: (Human) 1952
cilium movement
regulation of transcription, DNA-templated
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
nervous system development
axonogenesis
anterior/posterior pattern specification
Wnt signaling pathway
ventricular system development
neural plate anterior/posterior regionalization
regulation of cell-cell adhesion
regulation of protein localization
cerebrospinal fluid secretion
cell-cell adhesion mediated by cadherin
animal organ development
dendrite morphogenesis
Wnt signaling pathway, planar cell polarity pathway
cilium morphogenesis
motor neuron migration
plasma membrane bounded cell projection organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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