Search
Proteintech
NCAM1/CD56 Recombinant Rabbit Monoclonal Antibody (240078C9), CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
CL488-83365-6
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240078C9
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: LQVDIVPSQG EISVGESKFF LCQVAGDAKD KDISWFSPNG EKLTPNQQRI SVVWNDDSSS TLTIYNANID DAGIYKCVVT GEDGSESEAT VNVKIFQKLM FKNAPTPQEF REGEDAVIVC DVVSSLPPTI IWKHKGRDVI LKKDVRFIVL SNNYLQIRGI KKTDEGTYRC EGRILARGEI NFKDIQVIVN VPPTIQARQN IVNATANLGQ SVTLVCDAEG FPEPTMSWTK DGEQIEQEED DEKYIFSDDS SQLTIKKVDK NDEAEYICIA ENKAGEQDAT IHLKVFAKPK ITYVENQTAM ELEEQVTLTC EASGDPIPSI TWRTSTRNIS SEEKASWTRP EKQETLDGHM VVRSHARVSS LTLKSIQYTD AGEYICTASN TIGQDSQSMY LEVQYAPKLQ GPVAVYTWEG NQVNITCEVF AYPSATISWF RDGQLLPSSN YSNIKIYNTP SASYLEVTPD SENDFGNYNC TAVNRIGQES LEFILVQADT PSSPSIDQVE PYSSTAQVQF DEPEATGGVP ILKYKAEWRA VGEEVWHSKW YDAKEASMEG IVTIVGLKPE TTYAVRLAAL NGKGLGEISA ASEFKTQPVQ GEPSAPKLEG QMGEDGNSIK VNLIKQDDGG SPIRHYLVRY RALSSEWKPE IRLPSGSDHV MLKSLDWNAE YEVYVVAENQ QGKSKAAHFV FRTSAQPTAI PANGSPTSG
Target Information
CD56, also known as neural cell adhesion molecule (NCAM), is a highly glycosylated transmembrane glycoprotein of the immunoglobulin family. It plays a crucial role in cell adhesion, migration, axonal growth, pathfinding, and synaptic plasticity. CD56 is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa and is involved in homotypic adhesion of neural cells. It mediates interactions by binding extracellular matrix components such as laminin and integrins, with polysialic modification reducing CD56-mediated adhesion. In the hematopoietic system, CD56 is expressed on natural killer (NK) cells and a subset of T cells known as NKT cells. It is also found on most neuroectodermal-derived cell lines, tissues, and neoplasms, including retinoblastoma, medulloblastoma, astrocytomas, and neuroblastoma. CD56 serves as a widely used neuroendocrine marker with high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms, highlighting its importance in both neural and immune system functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 145 kda neural cell adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; CD-56; CD56; E NCAM; membrane glycoprotein; N CAM1; N-CAM; N-CAM-1; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule secreted isoform; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM; unnamed protein product
Gene Aliases: CD56; MSK39; NCAM; NCAM1
UniProt ID: (Human) P13591
Entrez Gene ID: (Human) 4684
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support