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          • Primary Antibodies ›
          • PEG3 Antibodies

          Proteintech

          PEG3 Recombinant Rabbit Monoclonal Antibody (241234C5), CoraLite® Plus 488

          View all (13) PEG3 antibodies

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          Cite PEG3 Recombinant Rabbit Monoclonal Antibody (241234C5), CoraLite® Plus 488

          Additional Information:
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          • Antibody Testing Data (1)
          PEG3 Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.
          PEG3 Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PEG3 Antibody (CL488-84030-5) in Flow

          1x10^6 HepG2 cells were intracellularly stained with 0.25 µg Coralite Plus 488 Peg3 Recombinant Antibody (CL488-84030-5, Clone: 241234C5) (red), or 0.25 µg CoraLite Plus 488 Rabbit IgG Isotype Control Recombinant Antibody (CL488-98136, Clone: 240953C9) (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF,00011). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          PEG3 Antibody in Flow Cytometry (Flow)
          PEG3 Recombinant Rabbit Monoclonal Antibody (241234C5), CoraLite® Plus 488

          Product Details

          CL488-84030-5

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          0.25 µg per 10^6 cells
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          241234C5

          Immunogen

          PEG3 fusion protein Ag20132
          3D Epitope / Immunogen

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1000 µg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Sequence of this protein is as follows: LNEHMRLHRE DDLLEQSQMA EEAIIPGLAL TEFQRSQTEE RLFECAVCGE SFVNPAELAD HVTVHKNEPY EYGSSYTHTS FLTEPLKGAI PFYECKDCGK SFIHSTVLTK HKELHLEEEE EDEAAAAAAA AAQEVEANVH VPQVVLRIQG LNVEAAEPEV EAAEPEVEAA EPEVEAAEPN GEAEGPDGEA AEPIGEAGQP NGEAEQPNGD ADEPDGAGIE DPEERAEEPE GKAEEPEGDA DEPDGVGIED PEEGEDQEIQ VEEPYYDCHE CTETFTSSTA FSEHLKTHAS MIIFEPANAF GECSGYIERA STSTGGANQA DEKYFKCDVC GQLFNDRLSL ARHQNTHTG

          Target Information

          In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: KIAA0287; Kruppel-type zinc finger protein; maternally imprinted; Paternally-expressed gene 3 protein; unnamed protein product; Zinc finger and SCAN domain-containing protein 24

          View more View less

          Gene Aliases: KIAA0287; PEG3; PW1; ZKSCAN22; ZNF904; ZSCAN24

          View more View less

          UniProt ID: (Human) Q9GZU2

          View more View less

          Entrez Gene ID: (Human) 5178

          View more View less

          Function(s)
          RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding zinc ion binding metal ion binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase II promoter apoptotic process regulation of gene expression positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.

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