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Proteintech
MTMR4 Recombinant Rabbit Monoclonal Antibody (241304E11), CoraLite® Plus 488
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Product Details
CL488-84328
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
241304E11
Immunogen
MTMR4 fusion protein Ag4310
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: SHQEQLSSVP DLTHGEEDIG KRGNNRNGQL LENPRFGKMP LELVRKPISQ SQISEFSFLG SNWDSFQGMV TSFPSGEATP RRLLSYGCCS KRPNSKQMRA TGPCFGGQWA QREGVKSPVC SSHSNGHCTG PGGKNQMWLS SHPKQVSSTK PVPLNCPSPV PPLYLDDDGL PFPTDVIQHR LRQIEAGYKQ EVEQLRRQVR ELQMRLDIRH CCAPPAEPPM DYEDDFTCLK ESDGSDTEDF GSDHSEDCLS EASWEPVDKK ETEVTRWVPD HMASHCYNCD CEFWLAKRRH HCRNCGNVFC AGCCHLKLPI PDQQLYDPVL VCNSCYEHIQ VSRARELMSQ QLKKPIATAS S
Target Information
MTMR, a member of the myotubularin family, encodes an intracellular protein of 1, 195 amino acids, and shares approximately 47% sequence identity with MTMR3, spiking to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781E194; FYVE domain-containing dual specificity protein phosphatase 2; FYVE-DSP2; MGC163449; MGC163451; MTMR7; Myotubularin-related protein 4; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4; Zinc finger FYVE domain-containing protein 11; zinc finger, FYVE domain containing 11
Gene Aliases: FYVE-DSP2; KIAA0647; MTMR4; ZFYVE11
UniProt ID: (Human) Q9NYA4
Entrez Gene ID: (Human) 9110
phosphatidylinositol-3-phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein binding
zinc ion binding
hydrolase activity
protein phosphatase binding
metal ion binding
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
binding, bridging
R-SMAD binding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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