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          • Primary Antibodies ›
          • PPAR gamma Antibodies

          Proteintech

          PPAR Gamma Monoclonal Antibody (4E12F10), CoraLite® Plus 647

          View all (24) PPAR gamma antibodies

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          Cite PPAR Gamma Monoclonal Antibody (4E12F10), CoraLite® Plus 647

          Additional Information:
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          • Antibody Testing Data (1)
          PPAR Gamma Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.
          PPAR Gamma Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PPAR Gamma Antibody (CL647-60127) in Flow

          1X10^6 K-562 cells were intracellularly stained with 0.2 µg CoraLite® Plus 647 Anti-Human PPAR Gamma (CL647-60127, Clone:4E12F10) (red), or 0.2 µg Isotype Control (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          PPAR Gamma Antibody in Flow Cytometry (Flow)
          PPAR Gamma Monoclonal Antibody (4E12F10), CoraLite® Plus 647

          Product Details

          CL647-60127

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          0.2 µg/1x10^6 cell suspension
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          4E12F10

          Immunogen

          Recombinant protein
          3D Epitope / Immunogen

          Conjugate

          CoraLite® Plus 647 CoraLite® Plus 647 CoraLite® Plus 647
          • CoraLite 555
          • CoraLite 594
          • CoraLite Plus 488
          • Request custom conjugation

          Excitation/Emission Max

          654/674 nm

          Form

          Liquid

          Purification

          Protein G

          Storage buffer

          PBS with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: NKCQYCRFQK CLAVGMSHNA IRFGRMPQAE KEKLLAEISS DIDQLNPESA DLRALAKHLY DSYIKSFPLT KAKARAILTG KTTDKSPFVI YDMNSLMMGE DKIKFKHITP LQEQSKEVAI RIFQGCQFRS VEAVQEITEY AKSIPGFVNL DLNDQVTLLK YGVHEIIYTM LASLMNKDGV LISEGQGFMT REFLKSLRKP FGDFMEPKFE FAVKFNALEL DDSDLAIFIA VIILSGDRPG LLNVKPIEDI QDNLLQALEL QLKLNHPESS QLFAKLLQKM TDLRQIVTEH VQLLQVIKKT ETDMSLHPLL QEIYKDLY

          Target Information

          This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: HUMPPARG; Nuclear receptor subfamily 1 group C member 3; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activator receptor, gamma; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor-gamma 5; peroxisome proliferator-activated receptor-gamma splicing; PPAR gamma; PPAR-gamma; PPARy; unnamed protein product

          View more View less

          Gene Aliases: CIMT1; FPLD3; GLM1; NR1C3; PPAR-gamma; PPAR-gamma2; PPARG; PPARG1; PPARG2; PPARG5; PPARgamma; PPARgamma2

          View more View less

          UniProt ID: (Human) P37231, (Mouse) P37238, (Rat) O88275

          View more View less

          Entrez Gene ID: (Human) 5468, (Mouse) 19016, (Rat) 25664

          View more View less

          Function(s)
          transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding nucleic acid binding DNA binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding prostaglandin receptor activity protein binding zinc ion binding enzyme binding peptide binding identical protein binding sequence-specific DNA binding metal ion binding retinoid X receptor binding arachidonic acid binding DBD domain binding LBD domain binding WW domain binding alpha-actinin binding R-SMAD binding E-box binding STAT family protein binding DNA-binding transcription factor binding RNA polymerase II regulatory region DNA binding core promoter sequence-specific DNA binding steroid hormone receptor activity transcription factor binding drug binding protein phosphatase binding estrogen receptor binding ligand-dependent nuclear receptor transcription coactivator activity activating transcription factor binding transcription regulatory region DNA binding C4 zinc finger nuclear receptor DNA-binding transcription factor zinc finger transcription factor gene-specific transcriptional regulator
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter placenta development regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter fatty acid metabolic process G-protein coupled receptor signaling pathway response to nutrient regulation of blood pressure hormone-mediated signaling pathway positive regulation of gene expression negative regulation of gene expression negative regulation of macrophage derived foam cell differentiation positive regulation of cholesterol efflux negative regulation of cholesterol storage negative regulation of lipid storage long-chain fatty acid transport negative regulation of angiogenesis cell differentiation monocyte differentiation BMP signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway intracellular receptor signaling pathway epithelial cell differentiation negative regulation of defense response response to nutrient levels positive regulation of cholesterol transport cellular response to insulin stimulus response to lipid peroxisome proliferator activated receptor signaling pathway glucose homeostasis regulation of circadian rhythm mRNA transcription from RNA polymerase II promoter negative regulation of MAPK cascade negative regulation of blood vessel endothelial cell migration innate immune response cell fate commitment positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of lipid metabolic process negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fatty acid metabolic process positive regulation of transcription from RNA polymerase II promoter retinoic acid receptor signaling pathway cell maturation rhythmic process negative regulation of smooth muscle cell proliferation negative regulation of inflammatory response white fat cell differentiation regulation of transport negative regulation of multicellular organismal process lipid homeostasis negative regulation of interferon-gamma-mediated signaling pathway negative regulation of SMAD protein import into nucleus positive regulation of adiponectin secretion cellular response to low-density lipoprotein particle stimulus cellular response to hypoxia negative regulation of mitochondrial fission positive regulation of lipoprotein transport nuclear receptor-mediated signaling pathway regulation of cellular response to insulin stimulus negative regulation of extracellular matrix assembly negative regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of cardiac muscle hypertrophy in response to stress negative regulation of cellular response to transforming growth factor beta stimulus positive regulation of adipose tissue development negative regulation of connective tissue replacement involved in inflammatory response wound healing negative regulation of vascular smooth muscle cell proliferation negative regulation of receptor signaling pathway via STAT positive regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular endothelial cell proliferation positive regulation of apoptotic signaling pathway negative regulation of cytokine production response to dietary excess diet induced thermogenesis negative regulation of acute inflammatory response transcription, DNA-templated transcription from RNA polymerase II promoter activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response signal transduction negative regulation of cell proliferation response to light stimulus regulation of gene expression negative regulation of receptor biosynthetic process negative regulation of sequestering of triglyceride regulation of lipid metabolic process fatty acid oxidation negative regulation of cell growth response to food response to retinoic acid negative regulation of collagen biosynthetic process lipoprotein transport positive regulation of apoptotic process steroid hormone mediated signaling pathway fat cell differentiation regulation of fat cell differentiation low-density lipoprotein particle receptor biosynthetic process positive regulation of fatty acid oxidation positive regulation of oligodendrocyte differentiation brown fat cell differentiation positive regulation of sequence-specific DNA binding transcription factor activity negative regulation of telomerase activity response to low-density lipoprotein particle positive regulation of phagocytosis, engulfment regulation of transcription involved in cell fate commitment cellular response to lithium ion cellular response to organic cyclic compound negative regulation of peptide hormone secretion negative regulation of cellular response to insulin stimulus negative regulation of pancreatic stellate cell proliferation heart development response to cold response to mechanical stimulus response to organic substance response to organic cyclic compound response to caffeine organ regeneration response to vitamin A response to immobilization stress response to diuretic response to drug response to starvation response to estrogen cellular response to retinoic acid cellular response to vitamin E cellular response to prostaglandin stimulus cellular response to prostaglandin E stimulus cellular response to hyperoxia response to metformin
          It has to be done as per old AB suggested Products section.

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