Predicted reactivity: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.
Positive control of Jurkat cell lysate or human kidney tissue suggested.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chloride channel ABP; Chloride intracellular channel protein 1; DADB-110M10.1; FLJ94671; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
Gene Aliases: Clcp; CLIC1; G6; NCC27
Molecular Function: RNA binding protein cytoskeletal protein epimerase/racemase isomerase nucleic acid binding oxidoreductase reductase signaling molecule transferase translation elongation factor translation factor