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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from a region between amino acids 62-111 of human CLIC1.|
|Storage buffer||PBS with 2% sucrose|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||4-8 µg/ml|
|Western Blot (WB)||1.25 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30044 detects CLIC1 from human samples.
PA1-30044 has been successfully used in immunohistochemistry (paraffin tissue), Western blot, and ELISA applications. Positive control of Jurkat cell lysate or human kidney tissue suggested.
The PA1-30044 immunogen is synthetic peptide derived from a region between amino acids 62-111 of human CLIC1.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Chloride channel ABP; Chloride intracellular channel protein 1; DADB-110M10.1; G6; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
CLIC1; G6; NCC27