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Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Chloride channel ABP; chloride intracellular channel 1; chloride intracellular channel protein; chloride intracellular channel protein 1; chloride intracellular channel protein 1 {ECO:0000250; Clcp; CLIC1; clic1 {ECO:0000312; CLIC1 protein; CLIC1; NCC27; DADB-110M10.1; EMBL:CAE83985.1, ECO:0000312; EMBL:CAE83985.1}; FLJ94671; G6; hRNCC; hypothetical protein LOC324481; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; regulatory nuclear chloride ion channel protein; RGD:1303043}; RNCC protein; UniProtKB:O00299, ECO:0000312; wu:fc30e04; zgc:77044
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