Search
Invitrogen
CLIC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
CLIC1 Antibody (PA5-109552) in WB
Western blot analysis of CLIC1 in extracts of various cell lines. Samples were incubated with CLIC1 Polyclonal antibody (Product # PA5-109552) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.
Product Details
PA5-109552
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 42-241 of human CLIC1 (NP_001279.2).
Conjugate
Form
Liquid
Concentration
2.58 mg/mL
Amount
258 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NVTTVDTKRR TETVQKLCPG GQLPFLLYGT EVHTDTNKIE EFLEAVLCPP RYPKLAALNP ESNTAGLDIF AKFSAYIKNS NPALNDNLEK GLLKALKVLD NYLTSPLPEE VDETSAEDEG VSQRKFLDGN ELTLADCNLL PKLHIVQVVC KKYRGFTIPE AFRGVHRYLS NAYAREEFAS TCPDDEEIEL AYEQVAKALK
Target Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 27kDa protein; Chloride channel ABP; Chloride intracellular channel protein 1; chloride intracellular channel protein 1 {ECO:0000250|UniProtKB:O00299, ECO:0000312|EMBL:CAE83985.1}; CLIC1; clic1 {ECO:0000312|EMBL:CAE83985.1, ECO:0000312|RGD:1303043}; DADB-110M10.1; FLJ94671; Glutaredoxin-like oxidoreductase CLIC1; Glutathione-dependent dehydroascorbate reductase CLIC1; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64 CLCP; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein; unnamed protein product
Gene Aliases: CL1C1; CLCNL1; Clcp; CLIC1; G6; NCC27
UniProt ID: (Human) O00299, (Mouse) Q9Z1Q5, (Rat) Q6MG61
Entrez Gene ID: (Human) 1192, (Mouse) 114584, (Rat) 406864
ion transport
chloride transport
signal transduction
ion transmembrane transport
positive regulation of osteoblast differentiation
regulation of mitochondrial membrane potential
platelet aggregation
chloride transmembrane transport
transport
regulation of ion transmembrane transport
regulation of cell cycle
regulation of anion transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support