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Proteintech
CLIC1 Polyclonal Antibody
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Product Details
14545-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CLIC1 Fusion Protein Ag6049 (1-241 aa encoded by BC064527)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEEQPQVE LFVKAGSDGA KIGNCPFSQR LFMVLWLKGV TFNVTTVDTK RRTETVQKLC PGGQLPFLLY GTEVHTDTNK IEEFLEAVLC PPRYPKLAAL NPESNTAGLD IFAKFSAYIK NSNPALNDNL EKGLLKALKV LDNYLTSPLP EEVDETSAED EGVSQRKFLD GNELTLADCN LLPKLHIVQV VCKKYRGFTI PEAFRGVHRY LSNAYAREEF ASTCPDDEEI ELAYEQVAKA LK (1-241 aa encoded by BC064527)
Target Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chloride channel ABP; Chloride intracellular channel protein 1; chloride intracellular channel protein 1 {ECO:0000250|UniProtKB:O00299, ECO:0000312|EMBL:CAE83985.1}; clic1 {ECO:0000312|EMBL:CAE83985.1, ECO:0000312|RGD:1303043}; DADB-110M10.1; FLJ94671; Glutaredoxin-like oxidoreductase CLIC1; Glutathione-dependent dehydroascorbate reductase CLIC1; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
Gene Aliases: Clcp; CLIC1; G6; NCC27
UniProt ID: (Human) O00299, (Mouse) Q9Z1Q5, (Rat) Q6MG61
Entrez Gene ID: (Human) 1192, (Mouse) 114584, (Rat) 406864
glutathione metabolic process
chloride transport
signal transduction
regulation of ion transmembrane transport
positive regulation of osteoblast differentiation
regulation of cell cycle
regulation of mitochondrial membrane potential
platelet aggregation
chloride transmembrane transport
transport
ion transport
regulation of anion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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