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Invitrogen
CNDP2 Polyclonal Antibody
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Product Details
PA5-83357
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CNDP2. Recombinant protein control fragment (Product #RP-102752).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AKWVAIQSVS AWPEKRGEIR RMMEVAAADV KQLGGSVELV DIGKQKLPDG SEIPLPPILL GRLGSDPQKK TVCI
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 95%.
Target Information
The CNDP2 gene encodes the protein carnosine dipeptidase 2, which belongs to the M20 metallopeptidase family and plays a critical role in the metabolism of dipeptides. CNDP2 is primarily involved in the hydrolysis of carnosine, a dipeptide composed of beta-alanine and histidine, and is expressed in various tissues, including the liver and kidney. This enzyme is significant in cellular processes related to nitrogen metabolism and the regulation of histidine-containing dipeptides, which have antioxidant properties influencing cellular redox balance. CNDP2 has implications in renal function and disease, where altered activity can impact the concentration of bioactive peptides involved in protective mechanisms against oxidative stress. Additionally, CNDP2 may have roles in metabolic diseases, such as diabetes and hypertension, where dipeptide regulation can influence metabolic pathways and cellular protection mechanisms. Ongoing research explores CNDP2's enzymatic activity, regulation, and potential therapeutic applications, particularly in conditions where modulation of peptide metabolism can offer clinical benefits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carnosine dipeptidase II; CNDP dipeptidase 2; Cytosolic non-specific dipeptidase; cytosolic nonspecific dipeptidase; epididymis secretory protein Li 13; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase
Gene Aliases: CN2; CNDP2; CPGL; HEL-S-13; HsT2298; PEPA
UniProt ID: (Human) Q96KP4
Entrez Gene ID: (Human) 55748
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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