This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
PA1-543 detects calciµm/calmodulin-dependent kinase I (CaMKI) from rat and mouse brain extract.
PA1-543 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~43 kDa protein representing CaMKI from rat and mouse brain extract.
PA1-543 immunizing peptide corresponds to amino acid residues 1-18 from human CaMKI protein. PA1-543 immunizing peptide (Cat. # PEP-134) is available for use in neutralization and control experiments.
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium/calmodulin-dependent protein kinase type 1; CaM kinase I; CaM kinase I alpha; CaM-KI; CAMK1-PEN; CaMKI-alpha; G alpha interacting protein; MGC120317; MGC120318; regulator of G-protein signalling 19
Gene Aliases: AI505105; Camk1; Camki; CaMKIalpha; D6Ertd263e; Gaip
Molecular Function: non-receptor serine/threonine protein kinase