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Invitrogen
Frizzled-2 Polyclonal Antibody
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Product Details
38-4700
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the N-terminal region of human and mouse Frizzled-2 (FZD2).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dfrizzled2; frizzled 2, seven transmembrane spanning receptor; frizzled family receptor 2; frizzled homolog 2; Frizzled-2; Fz-2; FzE2; polarity gene; putative
Gene Aliases: fz-2; Fz2; FZD2; fzE2; hFz2; OMOD2
UniProt ID: (Human) Q14332
Entrez Gene ID: (Human) 2535
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
sensory perception of smell
Wnt signaling pathway
neuron differentiation
non-canonical Wnt signaling pathway
endothelial cell differentiation
positive regulation of transcription, DNA-templated
hard palate development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
inner ear receptor cell development
ventricular septum morphogenesis
cochlea morphogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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