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This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
AL033370; AW456835; Dfrizzled2; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 2; frizzled 2, seven transmembrane spanning receptor; frizzled class receptor 2; frizzled family receptor 2; frizzled homolog 2; frizzled homolog 2 (Drosophila); frizzled-10; Frizzled-2; Fz10; fz-10; Fz2; Fz-2; Fzd10; Fzd2; fzE2; hFz2; Mfz10; Mfz10a; mFz2; rFz2
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