This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 11
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain.
Predicted reactivity: Mouse (90%), Pig (80%), Rhesus Monkey (97%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
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Protein Aliases: Alpha-glucosidase 2; carbohydrate processing enzyme of the endoplasmic reticulum; glucosidase II alpha-subunit; Glucosidase II subunit alpha; Neutral alpha-glucosidase AB
Gene Aliases: AU042638; G2AN; GANAB; GIIA; GLUII; KIAA0088; mKIAA0088
Molecular Function: glucosidase