Search
Bioss
GBA2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
BS-13297R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GBA2, amino acids 601-700.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 3.2.1.45; Beta-glucocerebrosidase 2; Beta-glucosidase 2; bile acid; bile acid beta-glucosidase; Bile acid beta-glucosidase GBA2; Bile acid glucosyl transferase GBA2; Cholesterol glucosyltransferase GBA2; Cholesteryl-beta-glucosidase GBA2; glucocerebrosidase 2; glucosidase, beta (bile acid) 2; Glucosylceramidase 2; NLGase; Non-lysosomal cholesterol glycosyltransferase; Non-lysosomal galactosylceramidase; Non-lysosomal glucosylceramidase; Non-lysosomal glycosylceramidase; unnamed protein product
Gene Aliases: AD035; F630034E04; GBA2; KIAA1605; NLGase; SPG46
UniProt ID: (Human) Q9HCG7, (Mouse) Q69ZF3
Entrez Gene ID: (Human) 57704, (Mouse) 230101, (Rat) 298399
galactosylceramidase activity
glucosylceramidase activity
hydrolase activity, hydrolyzing O-glycosyl compounds
beta-glucosidase activity
transferase activity
transferase activity, transferring glycosyl groups
hydrolase activity
hydrolase activity, acting on glycosyl bonds
glucosyltransferase activity
steryl-beta-glucosidase activity
catalytic activity
glucosidase
carbohydrate metabolic process
lipid metabolic process
sphingolipid metabolic process
glucosylceramide catabolic process
central nervous system development
steroid metabolic process
cholesterol metabolic process
bile acid metabolic process
glycoside catabolic process
central nervous system neuron development
lipid glycosylation
regulation of actin filament polymerization
regulation of microtubule polymerization
small molecule metabolic process
glycosphingolipid catabolic process
regulation of membrane lipid distribution
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support