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Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.
3.2.1.45; AD035; Beta-glucocerebrosidase 2; beta-glucosidase 2; bile acid; bile acid beta-glucosidase; Bile acid beta-glucosidase GBA2; Bile acid glucosyl transferase GBA2; Cholesterol glucosyltransferase GBA2; Cholesteryl-beta-glucosidase GBA2; F630034E04; GBA2; glucosidase beta 2; glucosidase, beta (bile acid) 2; glucosylceramidase 2; glucosylceramidase beta 2; Kiaa1605; NLGase; non-lysosomal glucosylceramidase; SPG46
200 µL
100 µL
50 µg
100 µL
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