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Abnova
GSC Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
GSC Antibody (H00145258-D01P) in WB
Western Blot analysis of GSC expression in transfected 293T cell line (H00145258-T01) by GSC MaxPab polyclonal antibody.
Lane 1: GSC transfected lysate(28.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: GSC transfected lysate(28.10 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00145258-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GSC (NP_776248.1, 1 a.a. approximately 257 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MPASMFSIDN ILAARPRCKD SVLPVAHSAA APVVFPALHG DSLYGASGGA SSDYGAFYPR PVAPGGAGLP AAVSGSRLGY NNYFYGQLHV QAAPVGPACC GAVPPLGAQQ CSCVPTPPGY EGPGSVLVSP VPHQMLPYMN VGTLSRTELQ LLNQLHCRRK RRHRTIFTDE QLEALENLFQ ETKYPDVGTR EQLARKVHLR EEKVEVWFKN RRAKWRRQKR SSSEESENAE KWNKTSSSKA SPEKREEEGK SDLDSDS
Target Information
This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GSC; Homeobox protein goosecoid
Gene Aliases: GSC; GSC1; SAMS
UniProt ID: (Human) P56915
Entrez Gene ID: (Human) 145258
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
gastrulation
anatomical structure morphogenesis
tissue development
neural crest cell fate specification
Wnt signaling pathway
dorsal/ventral neural tube patterning
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
forebrain development
middle ear morphogenesis
ear development
animal organ development
muscle organ morphogenesis
embryonic skeletal system morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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