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Invitrogen
H3K9ac Polyclonal Antibody
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H3K9ac Antibody (PA5-17868) in IHC
Immunohistochemistry was performed on cancer biopsies of human breast tissue. Paraffin-embedded tissue was stained with a polyclonal antibody against Acetyl-Histone H3 (Lys9) (Product # PA5-17868). Detection was performed using an anti-rabbit IgG secondary antibody and a colorimetric substrate.
Product Details
PA5-17868
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic acetylated peptide corresponding to residues surrounding Lys9 of histone H3.
Conjugate
Form
Liquid
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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