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          • Primary Antibodies ›
          • HAPLN4 Antibodies

          Bioss

          HAPLN4 Polyclonal Antibody

          View all (7) HAPLN4 antibodies

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          Cite HAPLN4 Polyclonal Antibody

          HAPLN4 Polyclonal Antibody

          Product Details

          BS-15412R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human HAPLN4, amino acids 21-120.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Hyaluronan and proteoglycan link protein 4 (HAPLN4), also known as Brain Link Protein 4 (BRAL1), is a gene located on chromosome 5q14.2, encoding a member of the link protein family that plays a crucial role in stabilizing interactions between hyaluronan and proteoglycans within the extracellular matrix. HAPLN4 is predominantly expressed in the brain, especially within the central nervous system where it contributes to the structural integrity and functional modulation of neural tissues. The protein is key in maintaining the organization of the extracellular matrix by binding hyaluronan and other matrix components, facilitating cell adhesion and signaling. This is vital for processes like neuronal migration, synapse formation, and neuronal differentiation during brain development. Variations in HAPLN4 expression or function are associated with neural developmental disorders and may influence the progression of neurodegenerative diseases due to its critical role in preserving the extracellular matrix architecture and neural connectivity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Brain link protein 2; brain linked protein 2; Hyaluronan and proteoglycan link protein 4; link protein 4

          View more View less

          Gene Aliases: 9330174O11; BRAL2; HAPLN4; KIAA1926; Lpr4

          View more View less

          UniProt ID: (Human) Q86UW8, (Mouse) Q80WM4

          View more View less

          Entrez Gene ID: (Human) 404037, (Mouse) 330790, (Rat) 361129

          View more View less

          Function(s)
          extracellular matrix structural constituent hyaluronic acid binding extracellular matrix glycoprotein
          Process(es)
          skeletal system development cell adhesion central nervous system development biological_process
          It has to be done as per old AB suggested Products section.
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