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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HARS Fusion Protein Ag9333 (1-282 aa encoded by BC011807) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MAERAALEE LVKLQGERVR GLKQQKASAE LIEEEVAKLL KLKAQLGPDE SKQKFVLKTP KGTRDYSPRQ MAVREKVFDV IIRCFKRHGA EVIDTPVFEL KETLMGKYGE DSKLIYDLKD QGGELLSLRY DLTVPFARYL AMNKLTNIKR YHIAKVYRRD NPAMTRGRYR EFYQCDFDIA GNFDPMIPDA ECLKIMCEIL SSLQIGDFLV KVNDRRILDG MFAICGVSDS KFRTICSSVD KLDKVSWEEV KNEMVGEKGL APEVADRIGD YVQQHGGVSL VEQ (1-282 aa encoded by BC011807)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dead end homolog 1; FLJ20491; HisRS; histidine translase; histidine tRNA ligase; Histidine--tRNA ligase, cytoplasmic; Histidyl-tRNA synthetase; histidyl-tRNA synthetase, cytoplasmic
Gene Aliases: CMT2W; Dnd1; HARS; HARS1; HRS; MMHRS; USH3B
UniProt ID: (Human) P12081, (Mouse) Q61035
Entrez Gene ID: (Human) 3035, (Mouse) 15115, (Rat) 307492
Molecular Function:
aminoacyl-tRNA synthetase
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