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Product Details
13333-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HK3 Fusion Protein Ag4148 (622-923 aa encoded by BC028129)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LLNWTKGFK ASDCEGQDVV SLLREAITRR QAVELNVVAI VNDTVGTMMS CGYEDPRCEI GLIVGTGTNA CYMEELRNVA GVPGDSGRMC INMEWGAFGD DGSLAMLSTR FDASVDQASI NPGKQRFEKM ISGMYLGEIV RHILLHLTSL GVLFRGQQIQ RLQTRDIFKT KFLSEIESDS LALRQVRAIL EDLGLPLTSD DALMVLEVCQ AVSQRAAQLC GAGVAAVVEK IRENRGLEEL AVSVGVDGTL YKLHPRFSSL VAATVRELAP RCVVTFLQSE DGSGKGAALV TAVACRLAQL TRV (622-923 aa encoded by BC028129)
Target Information
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP:D-hexose 6-phosphotransferase; hexokinase 3 (white cell); hexokinase iii; Hexokinase type III; Hexokinase-3; Hexokinase-C; Hexokinase3; HK III
Gene Aliases: HK III; HK-III; HK3; HKIII; HXK3; RNU73859
UniProt ID: (Human) P52790, (Rat) P27926, (Mouse) Q3TRM8
Entrez Gene ID: (Human) 3101, (Rat) 25060, (Mouse) 212032
cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
biological_process
hexose metabolic process
carbohydrate metabolic process
metabolic process
phosphorylation
negative regulation of hydrogen peroxide-mediated programmed cell death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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