This target displays homology in the following species: Cow: 93%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 79%; Rabbit: 100%; Rat: 93%
Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells. May act as a peptidase; experimental evidences are however required to confirm this prediction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-hydroxymethylcytosine (hmC) binding, ES cell-specific; Abasic site processing protein HMCES; Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; ES cell-specific 5hmC-binding protein; Peptidase HMCES; Putative endonuclease HMCES; putative peptidase SRAPD1; SRAP domain-containing protein 1; UPF0361 protein C3orf37; UPF0361 protein C3orf37 homolog
Gene Aliases: 8430410A17Rik; BOS_21232; C20H3orf37; C3orf37; C85376; DC12; HMCES; Srap1; SRAPD1