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Invitrogen
IL2RG Monoclonal Antibody (TUGh4)
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FIGURE: 1 / 2
IL2RG Antibody (MA562191) in Flow
Flow cytometry (surface staining) of IL2RG in human peripheral whole blood. Samples were incubated with IL2RG monoclonal antibody (Product # MA562191) using a dilution of 4 µg/mL. Separation of human lymphocytes (red-filled) from human CD132 negative blood debris (black-dashed).
Product Details
MA562191
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Rat
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
TUGh4
Immunogen
Human CD132-transfected cell line.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; IL2R gamma; interleukin 2 receptor gamma chain; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; p64
Gene Aliases: CD132; CIDX; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785, (Dog) P40321
Entrez Gene ID: (Human) 3561, (Dog) 403851
MAPK cascade
immune response
signal transduction
viral process
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
positive regulation of GTPase activity
interleukin-15-mediated signaling pathway
positive regulation of phagocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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