Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:4,000 | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KARS Fusion Protein Ag6778 (246-597 aa encoded by BC004132) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.31 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: IRSKIITYI RSFLDELGFL EIETPMMNII PGGAVAKPFI TYHNELDMNL YMRIAPELYH KMLVVGGIDR VYEIGRQFRN EGIDLTHNPE FTTCEFYMAY ADYHDLMEIT EKMVSGMVKH ITGSYKVTYH PDGPEGQAYD VDFTPPFRRI NMVEELEKAL GMKLPETNLF ETEETRKILD DICVAKAVEC PPPRTTARLL DKLVGEFLEV TCINPTFICD HPQIMSPLAK WHRSKEGLTE RFELFVMKKE ICNAYTELND PMRQRQLFEE QAKAKAAGDD EAMFIDENFC TALEYGLPPT AGWGMGIDRV AMFLTDSNNI KEVLLFPAMK PEDKKENVAT TDTLESTTVG TSV (246-597 aa encoded by BC004132)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 6.1.1.6; lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase
Gene Aliases: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; KARS; KARS1; KARS2; KIAA0070; KRS; LysRS; mKIAA0070
UniProt ID: (Human) Q15046, (Rat) Q5XIM7, (Mouse) Q99MN1
Entrez Gene ID: (Human) 3735, (Rat) 292028, (Mouse) 85305
Molecular Function:
aminoacyl-tRNA synthetase
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