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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
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